日本分子生物学会

Click here for MBSJ2016, the annual meeting in 2016 in Yokohama
GTC cover art July 2016

July 2016
見る者を揺さぶる、蝸牛の如き鳴門の渦潮

Naruto Strait, a strait between Shikoku and Awaji-shima Island, is famous for the huge Naruto-no-uzushio (Naruto whirlpools) that is generated by Japan's fastest current of sea water caused by the tide. It is thanks to the function of our inner ears that we can hear the roaring sound from and feel the acceleration of the rotation of the whirlpools. We saw an illusion of the structure of the inner ear (the semicircular canals, vestibule and cochlea) in a huge whirlpool that shook us by the inner ears.

GTC cover art June 2016

June 2016
QTL解析が解くイヌの百面相

Among phenotypes, quantitative traits are usually caused by many chromosomal loci (quantitative trait locus, QOL) in a complex manner, and researches using dogs have been fruitful. A number of dog breeds have been produced by human beings. The morphological character is highly variable among breeds, but uniformed within the same breed. Genome-wide association studies that coupled craniometric data obtained from various dog breeds have been conducted, and QTLs in which SNPs that might affect the skull shape existed concentratively were identified. One of the QTLs was mapped near BMP3 gene on Ch. 32, and it was shown that most breeds with shortened head had a common missense mutation in BMP3. Data on the background: Figure 3 of Schoenebeck et al. (2012) PLoS Genet. 8, e1002849 (DOI: 10.1371/journal.pgen.1002849). Upper panel: SNP distribution around BMP3 locus among various dog breeds. Lower panel: Plots of important SNPs (conserved, exonic, etc.) extracted from the upper panel.