Fukuwarai is a traditional Japanese New Year's game in which blindfolded players compete on how well or strangely they can create faces by placing cut-out facial parts (eyes, nose, etc.) on paper with an outline of a face. What these women are enjoying is a fukuwarai with cell organelles likened to facial parts. Now, what kind of cells will they make?
Two pairs of “look-alikes” that match SNPs. Comparisons of multi-omics and lifestyle were made between look-alikes who were not genetically related but had similar faces (Joshi et al. (2022) Cell Reports 40: 111257, DOI: 10.1016/j.celrep.2022.111257). The results showed that among pairs of “look-alike,” the rate of matching SNPs related to facial features was high. In addition, height, weight, smoking habits, and education also had correlations. On the other hand, DNA methylome and microbiome were not similar. This study may provide clues as to how much the extent to which the genome sequence and environmental factors contribute to physical and behavioral traits.