The single-cell RNA-sequencing technology has a possibility of changing biological studies completely. This is a schematic image of the technology. As with petals of the cherry blossoms, for example, even a number of early embryonic cells indistinguishable from each other can be clustered and visualized based on gene expression data, just as the image is projected on the water surface, and then further analysis can be progressed. Data: Dr. Takefumi Kondo and Mr. Shunta Sakaguchi (Kyoto University).
This is the 'Spindle Checkpoint' placed at the important point 'Metaphase-Anaphase Transition' in the post town 'M Phase' on the 'Cell Cycle Highway.' The mitotic spindles and chromosomes carried by the travelers are carefully inspected, and the travelers must be arrested until all the chromosomes have been aligned at the equator and all the pairs of sister kinetochores have been properly attached to the microtubules from both poles of the spindle to achieve bi-orientation. Only those who safely pass the checkpoint can enter the 'anaphase' of their trips.