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Job description: The International Research Center for Medical Sciences (IRCMS) was established in 2015 as the center of excellence in Kumamoto University for world-class research in life sciences through the internationalization of its research environment and the establishment of global collaborations. The Center features an open lab layout with few walls and partitions between labs to facilitate communication among scientists. English is the official language for all seminars and lab meetings to promote international scientific discourse. The laboratory of Proteostasis in Stem Cell was newly establshed in 2021. We conduct research in hematology (especially hematopoietic stem cell biology and erythropoiesis) and fetal development. In this particular project, the successful candidate is expected to actively conduct our ongoing projects investigating roles of maternal environment in fetal organ formation. The lab is a part of International Research Center for Medical Sciences (IRCMS), so that the researcher will have a full access to our core facility and common research activities.

Available positions: Postdoctoral fellow (1-2 positions), up to 3 years. The successful candidate is expected to start as soon as possible.

Address of work location: International Research Center for Medical Sciences, Kumamoto University, 2-2-1 Honjo, Chuo-ku, Kumamoto City 860-0811, Japan

Treatment after recruitment: Compensation will be decided according to an assessment of the candidate based on her/his experiences and scientific achievements as well as Kumamoto University's regulation.

Qualifications needed for this position: Applicants need to hold Ph.D degree (when starting). It is desired to have experiences working in the life science field, holding skills to handle animal models (mice), and sufficient communication skills in English.
Following experiences could be advantages:having studied in hematology field; skills to use flow cytometers; skills to perform histological analyses.

Application documents: Interested applicants are encouraged to assemble following documents and submit as an application packet to kenmiharada(at)kumamoto-u.ac.jp

1. Letter of intent

2. Curriculum vitae with e-mail address, photo and contact information

3. A brief description of candidate's previous research

4. A statement of research accomplishment

5. A list of publication

6. Contact information of 2 references

Selection details: Upon paper selection, top applicants will be invited for an interview (via Skype or Zoom) and the final result will be noticed via e-mail address.

Contact information:
Kenichi Miharada, Ph.D.
Professor , Lab of Proteostasis in Stem Cell
International Research Center for Medical Sciences, Kumamoto University
2-2-1 Honjo, Chuo-ku, Kumamoto 860-0811, Japan
E-mail: kenmiharada(at)kumamoto-u.ac.jp
Tel/Fax: +81-96-373-6885

2022-11-01 2023-02-01

Open positions
Team Leader (Principal Investigator)
One position

Qualifications
1.A holder of Ph.D. or equivalent degree.
2.Has relevant knowledge, experience and ability to oversee and carry out the research projects outlined under Research Field.

Work location
RIKEN Center for Biosystems Dynamics Research (Kobe Campus-East-West)
2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan

Research field
The RIKEN Center for Biosystems Dynamics Research (BDR) aims to understand the general principles of living systems through unraveling the temporal and spatial dynamics of biological phenomena unfolding over the course of their lifespan from development and birth to aging and death. Researchers at the Center use a wide range of interdisciplinary approaches to address this overarching theme such as imaging, multi-omics, theory, molecular biology, stem cell biology, organoids, and the use of diverse animal models.
RIKEN BDR is now actively recruiting a talented Team Leader (Principal Investigator) who conducts challenging and innovative research to pioneer new fields of life cycle science, which aims to understand the biological phenomena related to the progression and transition of various life stages (from development and birth to aging and death). We welcome any research that will lead to conceptual advances in understanding the life cycle. Topics can include how organisms control life stage transitions, how they achieve long-term control across distinct life stages, metabolic/epigenetic/morphogenetic transitions in the life cycle, multi-organ interactions, stem cell-based tissue maintenance, homeostasis, cell-to-cell communication, transgenerational interactions (e.g. mother-to-fetal communication), and aging. We also welcome the incorporation of approaches that promote life cycle science, such as combining organ reconstruction methods, comparative studies of diverse animal models and primates including human subjects, approaches linking events at multiple scales from molecules to cells as well as tissues and organs, and implementation of other cutting-edge technologies.
- Opportunities provided by BDR -
BDR provides early-career PIs with an excellent environment for their independent research, including internationally competitive start-up packages and annual research funds as well as mentoring by experienced senior BDR PIs. New PIs will be provided with approximately 150 m2 of dedicated space for their laboratory and will also have the use of common equipment areas shared with other laboratories. All BDR researchers have access to cutting-edge facilities such as those for various animal models, mouse genome engineering, multi-scale imaging, omics, and structural biology. PIs will also have opportunities for active collaborations with medical institutions and industry, and for mentoring graduate students through several joint graduate school programs with affiliated graduate schools.
For more information, please visit the BDR website / PI recruitment introduction.

BDR website https://www.bdr.riken.jp/en/index.html

PI recruitment introduction https://www.bdr.riken.jp/en/career/jobs/pi.html

We welcome applications from women of any nationality to apply. RIKEN is actively undertaking initiatives to promote gender equality and diversity, and moving forward to establish a more diverse and vibrant research environment. In compliance with Article 8 of the Equal Employment Opportunity Law (Special Provisions of Measures Pertaining to Women Workers), this type of recruitment is carried out as a measure to attain adequate levels of female representation. The working language for all discussions open to BDR members is English.

Deadline
We will start reviewing applications received by noon on December 20, 2022 (Japan Standard Time).
The recruitment will continue until the position is filled.

Start of employment
Negotiable

Details
For more information and required application documents, please visit the application website:
https://www.riken.jp/en/careers/researchers/20221017_1/index.html

2022-10-18 2022-12-20

Anton lab in the Neuroscience Center at the University of North Carolina School of Medicine (https://www.antonlab.org) and Yasuda lab at the Max Planck Institute for Neuroscience, Florida (https://mpfi.org/science/our-labs/yasuda-lab) are seeking highly motivated post-doctoral fellows interested in investigating the molecular mechanisms of cerebral cortical circuit development and neurodevelopmental disorders, particularly the role of the cellular antenna (i.e., primary cilia) in this process (see Neuron, 2020, DOI: 10.1016/j.neuron.2019.11.028; Curr Opin Neurobiol, 2021, DOI: 10.1016/j.conb.2021.02.002; Developmental Cell 2020, doi.org/10.1016/j.devcel.2019.11.005; Neuron, 2022, DOI: 10.1016/j.neuron.2022.01.034). Opportunities are available to investigate the molecular mechanisms of neural circuit development and function in the mammalian brain and in neurodevelopmental disorders using advanced multi-modal methods, including, but not limited, to circuit mapping, chemogenetic and optogenetic manipulation of signaling pathways, CRISPR-Cas9 based genome editing, single-cell transcriptomics, brain organoids, and human cortical connectomics. Anton and Yasuda labs provide an exceptionally supportive environment designed to facilitate career growth and path to independence. Postdoctoral fellows will have the advantage of being jointly mentored by both PIs. Ambitious, driven candidates with a recent Ph.D. (and/or MD) in molecular biology, cell biology, genetics, neuroscience, or related field with a solid thesis publication record are encouraged to apply. Please send CV and a brief cover letter of interest to Dr. E. S. Anton or Dr. Ryohei Yasuda via e-mail: anton[at]med.unc.edu or ryohei.yasuda[at]mpfi.org (*Please replace [at] with @ when addressing Emails). University of North Carolina and Max Planck Institute, Florida are EEO/AA employers and encourage applications from minorities and women.

2022-09-05 2022-12-05

URL: https://cbs.riken.jp/career-brain-science/

The RIKEN Center for Brain Science (CBS) is Japan’s premier neuroscience research center. Taking advantage of the multidisciplinarity of the fields of medicine, biology, chemistry, engineering, mathematical sciences, and psychology, our aim is to advance basic research and develop innovative technologies for elucidating the functions of the brain and the mind at multiple levels from genes, molecules, cells and whole organisms to societal systems. We also aim at finding solutions to the issues which contemporary society confronts, e.g. how we grapple with the psychological ramifications of our own inventions such as artificial intelligence (AI) and big data, and how we seek solutions to conquer diseases such as depression and dementia. For details, please refer to the RIKEN CBS website. https://cbs.riken.jp/en/

【Open Positions】
Team Leader (Principal Investigator position); Approximately 3 persons (half or more will be women)

【Job description】
Since its foundation in April 2018 following the strong 20-year foundation of its predecessor, the Brain Science Institute (BSI), to achieve the main research goals as described below, CBS has continuously endeavored for setting up the state-of-art research environments such as by installation of 7T fMRI for the study of human brain. This year, we are looking for researchers as Team Leaders (principal investigators) who can make the best of this excellent research environment by collaborating closely with researchers inside and outside CBS with diverse expertise to comprehensively promote research on brain and mind across multiple levels. The new team leader will supervise the laboratory and work as a "research manager" to train and guide researchers and other staffs. We are seeking a broad range of applicants in the fields of brain science and related fields. In order to further promote the diversity of researchers, which is one of CBS's strengths, we will ensure that at least half of the new hires will be women.
Four major themes of CBS:
1. Research to reveal the high-level cognitive functions of the human brain
Our goal is to decipher how we reflect on ourselves, make inferences, and predict what others are thinking.
2. Multi-layered studies based on animal models
By conducting research at all levels, we aim to understand the principles of brain functions and brain-body interactions.
3. Data-driven research led by theoretical and technological advances
Ever larger and complex data acquired with advanced technologies can be harnessed to develop new theories and more universal and efficient AI systems.
4. Developing diagnostic and therapeutic methods for neuropsychiatric disorders
We aim to address the social challenges of brain diseases and to create seeds for innovations that will enhance the quality of life.

【Qualification】
University graduates with a PhD, although doctoral degrees are not a prerequisite
Ability to conduct world-class research by taking advantage of the excellent research environments of CBS and RIKEN
Possess leadership skills and management ability in the laboratory and the research community

【Work Location】
RIKEN Wako (2-1 Hirosawa, Wako, Saitama 351-0198)

【Start of Employment】
April 1st, 2023 or later (negotiable)

【Application and Required Documents】
Please check the URL above.

【How to apply】
Please check the URL above.

【Deadline】
Applications and letters of recommendation must arrive by 5 pm on November 15, 2022 (Japan time).

【Contact Information】
CBS Search Committee Administrative Office, RIKEN Center for Brain Science (CBS)
2-1 Hirosawa, Wako, Saitama 351-0198
Inquiries will be accepted by the following e-mail.
E-mail: cbs-search[at]ml.riken.jp (Replace [at] with @)

2022-08-24 2022-11-15

The Srinivasan Lab at Oklahoma Medical Research Foundation (OMRF) is recruiting motivated researchers to conduct NIH supported research about heart valves. Heart valves open and close approximately 40 million times a year and are critical for our wellbeing. Valve defects are observed in ~ 2.5% of all individuals, increasing to ~8% in individuals >65 years old and ~13% in those who are >75. The ageing population is rapidly increasing in the world, which in turn is expected to raise the frequency of heart valve disorders. Therefore, we urgently need better understanding of heart valve diseases to stop or slow the progression of heart valve disease. Towards this goal the Srinivasan lab uses state of the art biochemical, cell biological and transgenic technologies to dissect the roles of transcription factors and signaling molecules that regulate valve development and disease.

Please check our latest publications: Cha et al (2016) Genes Dev. (cover image) June 16; 30: 1-16; Cha et al (2018) Cell Reports. (cover image) October 16; 25(3):571-584; Mahamud et al (2019) Development. November 5;146(21):dev184218; Geng et al (2020) JCI Insight. (cover image) July 23;5(14):e137652; Chen et al (2020) Development. (cover image) Dec 7;147(23):dev192351, and Cha et al (2020) Development. (cover image) Dec 13;147(23):dev195453.

The ideal candidate will be enthusiastic about challenging projects and will have experience with Cell Biology, Molecular Biology, Biochemistry or Immunology. Experience with mouse models is preferred.

Required Qualifications

Postdoctoral Fellow/Staff Scientist: Ph.D., M.D., or Ph.D./M.D.

Research Technician: Undergraduate degree and above.

Salary of postdoctoral fellows is according to the stipulation of NIH. Salary of the Staff Scientist/Research Technician will be commensurate with experience. Preference will be given to candidates with publications in respected journals. Please send CV, list of 3 references, reprints of publications and a brief summary of interests and career goals to Sathish-srinivasan[at]omrf.org (*Please replace [at] with @ when addressing Emails).

OMRF is an independent, not-for-profit, biomedical research institute in Oklahoma City, USA. OMRF has been selected as one of the best research institutions for post-docs in the USA by The Scientist journal. Oklahoma City metropolitan area offers affordable housing, low cost of living, great public schools and numerous recreational activities. Additional information about OMRF can be found at http://omrf.org. Please check the Srinivasan lab website for more information about our research: https://srinivasan.omrf.org/

2022-07-28 2022-12-31

The Srinivasan Lab at Oklahoma Medical Research Foundation (OMRF) is recruiting motivated researchers to conduct NIH supported research to study lymphatic vascular development and disease. Lymphatic vasculature returns interstitial fluid, immune cells and digested lipids to blood and is crucial to support the function of the circulatory, immune and digestive systems. A dysfunctional lymphatic vasculature causes interstitial fluid to accumulate in tissues, leading to chronic swelling (lymphedema). Lymphatic defects are also implicated in systemic inflammation, cardiovascular disease and metabolic syndrome. Yet, therapeutic approaches are not available to treat lymphatic diseases. Towards this goal the Srinivasan lab uses state of the art biochemical, cell biological and transgenic technologies to dissect the roles of transcription factors and signaling molecules that regulate lymphatic vascular development and disease.

Please check our latest publications: Cha et al (2016) Genes Dev. (cover image) June 16; 30: 1-16; Cha et al (2018) Cell Reports. (cover image) October 16; 25(3):571-584; Mahamud et al (2019) Development. November 5;146(21):dev184218; Geng et al (2020) JCI Insight. (cover image) July 23;5(14):e137652; Chen et al (2020) Development. (cover image) Dec 7;147(23):dev192351, and Cha et al (2020) Development. (cover image) Dec 13;147(23):dev195453.

The ideal candidate will be enthusiastic about challenging projects and will have experience with Cell Biology, Molecular Biology, Biochemistry or Immunology. Experience with mouse models is preferred.

Required Qualifications

Postdoctoral Fellow/Staff Scientist: Ph.D., M.D., or Ph.D./M.D.

Research Technician: Undergraduate degree and above.

Salary of postdoctoral fellows is according to the stipulation of NIH. Salary of the Staff Scientist/Research Technician will be commensurate with experience. Preference will be given to candidates with publications in respected journals. Please send CV, list of 3 references, reprints of publications and a brief summary of interests and career goals to Sathish-srinivasan[at]omrf.org (*Please replace [at] with @ when addressing Emails).

OMRF is an independent, not-for-profit, biomedical research institute in Oklahoma City, USA. OMRF has been selected as one of the best research institutions for post-docs in the USA by The Scientist journal. Oklahoma City metropolitan area offers affordable housing, low cost of living, great public schools and numerous recreational activities. Additional information about OMRF can be found at http://omrf.org. Please check the Srinivasan lab website for more information about our research: https://srinivasan.omrf.org/

2022-07-28 2022-12-31