Job title, available positions: Team Leader, one position
• Development of efficient identification method of genomic mutations both computationally and experimentally
• Technical operation of genome analysis platform
• Analysis of genomic mutants induced by heavy-ion irradiations
• Evolutionary studies, epigenetics research and gene expression control research using chromosome structure change by beam irradiation
Deadline: 17:00(JST), March 31, 2020
Start of Employment: October 1, 2020 (Negotiable)
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A postdoc opportunity is available to study hepatic fibrosis in the lab of Dr. Jennifer Chen, Assistant Professor, Department of Medicine, Division of Gastroenterology and Hepatology at University of California, San Francisco.
The lab studies novel mechanisms of hepatic stellate cell inactivation and fibrosis regression. The lab has identified and validated several antifibrotic targets using in vitro and in vivo models of hepatic fibrosis. The lab is also developing novel small molecule inhibitors to target these identified pathways.
Applicants should submit a brief statement  explaining their interest in the position, a curriculum vita  and the contact information of three references  by email directly to Dr. Jennifer Chen at Jennifer.Chen4@ucsf.edu
DESIRED SKILLS AND EXPERIENCE The ideal candidate should have a PhD or equivalent degree in molecular biology or other related fields with a strong foundation in cell biology, biochemistry and mouse models of injury and fibrosis. The candidate should have strong publication record in international journals, possess good written and verbal communication skills, and be able to work independently and collaboratively within a research team. The candidate should be proficient in experimental mouse models and standard biological techniques (protein biochemistry, molecular biology, cell biology, tissue culture and pathology).
Postdoctoral Position – Tumor Microenvironment and Metastasis –
St Jude Children's Research Hospital, Memphis, TN, USA
A fully funded postdoctoral position is available in the laboratory of Dr. Myriam Labelle at St. Jude Children’s Research Hospital in Memphis, TN, USA. The Labelle laboratory studies the role of the microenvironment in cancer progression and metastasis, with major efforts dedicated to elucidating the molecular mechanisms by which blood platelets, granulocytes, and the extracellular matrix (ECM) cooperate to promote metastasis (Cancer Cell, 20(5):576-90, 2011; PNAS, 111(30):E3053-61, 2014). In recent work (EMBO J, 38(16):e101302, 2019), we discovered that WISP1, a factor secreted by tumor cells upon interactions with platelets, promotes metastasis by inducing collagen linearization in tumors. We are now interested in further understanding the molecular basis of platelet-tumor cells and WISP1-ECM interactions and how they can be targeted to prevent cancer metastasis and improve the survival of cancer patients. Current studies are conducted leveraging a wide array of model systems and techniques including novel mouse models of metastasis, patient-derived xenografts, in vitro co-culture systems, and advanced microscopy approaches.
We are looking for a highly motivated and organized individual to join our team. The applicant should have strong communication skills, the ability to work independentlyand as part of collaborative research efforts, and a strong desire to make a major contribution to the field of cancer metastasis.
St Jude Children's Research Hospital offers an outstanding research environment, state-of-the-art scientific resources and facilities, and a community of highly collaborative investigators.
Please send a cover letter describing research interests and accomplishments, CV and the names and addresses of three references to email@example.com.
Seeking a Research Scientist
Laboratory for Prediction of Cell Systems Dynamics (PI: Katsuyuki Shiroguchi), RIKEN Center for Biosystems Dynamics Research
Start of Employment:
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