Vol. 28, No. 4(April 2023)

Wnt2022, an international conference on Wnt research, was held on November 15 to 19, 2022, in Awaji Island (Hyogo Prefecture). This memorable gathering was the first Wnt meeting in Japan and Asia, finally held in person after being postponed for two years due to COVID-19. The cover of this issue features Himeji Castle (Himeji, Hyogo Prefecture) (*CG fiction) with an exceptional decoration showing the name of the meeting and the names of important components of Wnt signaling, to commemorate this occasion. The Meeting Report in this issue detailed the discussion at the conference and its connection to Himeji Castle (Kikuchi et al. (2023) Genes Cells, 28: 249-257, DOI: 10.1111/gtc.13014).

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Genes to Cells © 2023 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 28, Issue 4, 2023.

Meeting Report

Pages: 249-257 Wnt 2022（EMBOワークショップ|山田カンファレンス）ミーティングレポート Wnt 2022 EMBO | the Company of Biologists workshop and Yamada conference 菊池　章、高木　淳一、高田　慎治、石谷　太、南　康博 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13014

Original Articles

Pages: 258-266 霊長類におけるタンパク質間相互作用と遺伝子必須性を介したリガンドと受容体の進化的特徴 Evolutionary features of ligands and their receptors via protein-protein interactions and essentiality in primates 回渕　修治、原本　悦和、池田　望、伊藤　道彦 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13006

Pages: 267-276 GM-CSF産生CCR2⁺CCR6⁺Th17細胞はデキストラン硫酸ナトリウム誘発大腸炎モデルマウスにおいて病原性を示す GM-CSF-producing CCR2⁺CCR6⁺ Th17 cells are pathogenic in dextran sodium sulfate-induced colitis model in mice 有木　晋平、小坂　聡太郎、佐知　望美、Thanyakorn Chalalai、曽我　泰裕、福田　千瑛、鹿子嶋　洋明、Supanuch Ekronarongchai、水上　一弘、神山　長慶、村上　和成、小林　隆志 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13008

Pages: 277-287 HOXB7はSTAT3を介して、NMuMG細胞におけるトランスフォーメーションと肺転移を誘導する HOXB7 induces STAT3-mediated transformation and lung metastasis in immortalized mammary gland NMuMG cells 東　和志、坂本　舞、片山　翔太、松井　貴香、中道　和也、五島　直樹、渡辺　慎哉、中山　淳、仙波　憲太郎 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13009

Pages: 288-306 弱い放射線が引き起こす細胞ストレスや傷害の解析法：細胞ライセートアレイ法 Analysis method of cellular stress caused by intermediate dose-rate irradiation using a cell lysate array technique 森島　信裕、緒方　裕光、馬替　純二、伊藤　嘉浩、小林　純也 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13011

Pages: 307-318 Ror1受容体はアストロサイトにおいてPPARαを介した脂肪酸代謝を促進する Ror1 promotes PPARα-mediated fatty acid metabolism in astrocytes 田中　祐紀、南　康博、遠藤　光晴 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13013

Brief Report

Pages: 319-325 アルツハイマー病患者由来神経細胞におけるオートファジーの異常はＡβ産生阻害で緩和される Alterations of ATG4A and LC3B in neurons derived from Alzheimer's disease patients 城谷　圭朗、渡辺　かおり、八田　大典、久徳　弓子、大澤　裕、砂田　芳秀、近藤　孝之、井上　治久、岩田　修永 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13010