Vol. 28, No. 2(February 2023)

Urashima Taro, the protagonist of a Japanese fairy tale, returned from his undersea utopia with his youth intact after hundreds of years, but as soon as he was exposed to the smoke from the souvenir Tamatebako (jeweled box), he turned into an old man. This painting depicts how the smoke causes Urashima Taro to lose not only his youth but also the Y chromosome in a part of his cells. Mosaic loss of chromosome Y (mLOY) is commonly observed in older men and has been linked to ageing and cancer, and has also been found to increase the risk of heart disease (Sano et al. (2022) Science 377: 292-297, DOI: 10.1126/science.abn3100). We referred to Fukami & Miyado (2022) Reprod. Med. Biol. 21: e12445, DOI: 10.1002/rmb2.12445 for the depiction of chromosomes.

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Genes to Cells © 2023 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 28, Issue 2, 2023.

Original Articles

Pages: 83-96 GPR56のC末端フラグメントは神経細胞において別のAdhesion GPCRであるLatrophilin1 (LPHN1)のN末端フラグメントが受け取ったシグナルを伝える GPR56 C-terminal fragment mediates signal received by N-terminal fragment of another adhesion GPCR Latrophilin1 in neurons 野島　悠祐、鳥山　真奈美、多胡　憲治、水野　憲一、森下　和広、伊東　広 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12994

Pages: 97-110 線虫Caenorhabditis elegansの二つのダイニン中間鎖DYCI-1とWDR-60にはそれぞれ特有の機能がある Dynein intermediate chains DYCI-1 and WDR-60 have specific functions in Caenorhabditis elegans 東田　真季、丹羽　伸介 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12996

Pages: 111-128 細胞質長鎖ノンコーディングRNAのdutAは細胞性粘菌のSTATaシグナルと発生の運命拘束に影響する The cytosolic lncRNA dutA affects STATa signaling and developmental commitment in Dictyostelium 嵯峨　幸夏、下山　雄大、山田　葉子、森川　直樹、川田　健文 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12997

Pages: 129-148 Spo11を欠損した減数分裂における染色体依存的な異数体形成 Chromosome-dependent aneuploid formation in Spo11-less meiosis 川島　友莉、小田　有沙、疋田　泰士、太田　邦史 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12998

Pages: 149-155 内在性レトロウイルスwalbからのサテライトDNAの形成はアカクビワラビーのみで起こったと推測される Marsupial genome analysis suggests that satellite DNA formation from walb endogenous retrovirus is an event specific to the red-necked wallaby 古賀　章彦、橋本　顕嗣、本田　祐介、西原　秀典 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12999

Pages: 156-169 コモンマーモセット胚性幹細胞からの拡大多能性幹細胞誘導の試み Attempts for deriving extended pluripotent stem cells from common marmoset embryonic stem cells 吉松　祥、中嶋　舞高、孫　怡姫、夏目　里恵、崎村　建司、中務　胞、笹岡　俊邦、中村　真理、芹澤　崇、佐藤　月花、佐々木　えりか、Hongkui Deng、岡野　栄之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13000