Vol. 27, No. 9(September 2022)

ラボ用汎用ヒト型からくりロボット
A general-purpose humanoid karakuri ningyo (puppet) robot that accurately dispenses reagents. Saving labor is not the only thing such general-purpose robots for laboratories can do. The reproducibility of research could be dramatically improved by quantifying human skills and experience and setting them to robots. It will also facilitate scaling up of research. Sharing of programs (protocols) could make it easier for everyone to try highly challenging experiments.

Genes to Cells © 2022 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 27, Issue 9, 2022.

Original Articles

Pages: 549-558
ヒト化抗ポドプラニンCAR導入細胞傷害性T細胞は固形腫瘍動物モデルにおいて優れた抗腫瘍効果を示す
Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in an animal model

石川 晃大、早稲田 真澄、石井 智子、金子 美華、加藤 幸成、金子 新
https://onlinelibrary.wiley.com/doi/10.1111/gtc.12972

Pages: 559-567
黄色ブドウ球菌スーパー抗原様毒素SSL12のマスト細胞活性化にかかわる責任アミノ酸残基の同定
Identification of responsible amino acid residues in staphylococcal superantigen-like 12 for the activation of mast cells

金 光東、伊藤 佐生智、伊藤 佑真、大矢 進、肥田 重明
https://onlinelibrary.wiley.com/doi/10.1111/gtc.12973

Pages: 568-578
海洋性ビブリオ菌のべん毛モーター回転子タンパク質FliMの変異による多べん毛形成
Formation of multiple flagella caused by a mutation of the flagellar rotor protein FliM in Vibrio alginolyticus

本間 道夫、竹川 宜宏、藤原 和志、郝 雨希、尾上 靖宏、小嶋 誠司
https://onlinelibrary.wiley.com/doi/10.1111/gtc.12975

Brief Report

Pages: 579-585
GW182のAgo結合ドメインにはCCR4-NOT複合体と結合するW残基に富んだ領域が存在する
N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex

脇山 素明、滝元 宏治
https://onlinelibrary.wiley.com/doi/10.1111/gtc.12974