Vol. 27, No. 7(July 2022)

Dyed cloths are hung out to dry and flutter coolly. Those cloths represent human 22 autosomes and X chromosome. Although it has been a long time since most of the human genome was sequenced, there were still many unresolved parts (the colored parts of the cloths in this drawing), such as telomere, centromere, ribosomal DNA, and segmental duplications. Thanks to the efforts of researchers and advances in technology, the sequencing of all bases except the Y chromosome has been finally achieved (Nurk et al. (2022) Science 376: 44-53, DOI: 10.1126/science.abj6987).

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Genes to Cells © 2022 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 27, Issue 7, 2022.

Review Article

Pages: 469-481 The structure-function analysis of Obg-like GTPase proteins along the evolutionary tree from bacteria to humans Asmita Chakraborty, Sheta Halder, Purvi Kishore, Disha Saha, Sujata Saha, Kunal Sikder and Arnab Basu https://onlinelibrary.wiley.com/doi/10.1111/gtc.12942

Original Articles

Pages: 482-492 1'-acetoxychavicol acetateによる細菌リポ多糖を介した炎症応答の抑制 Inhibition of lipopolysaccharide-induced inflammatory responses by 1'-acetoxychavicol acetate Ong Guang Han、織　大祐、川﨑　拓実、河合　太郎 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12943

Pages: 493-504 ループスモデルマウスの体内で低値を示すパルミトイルエタノールアミドは、Toll様受容体9を介する炎症を抑制する　－液体クロマトグラフ質量分析法による網羅的解析－ Comprehensive lipidomics of lupus-prone mice using LC-MS/MS identifies the reduction of palmitoylethanolamide that suppresses TLR9-mediated inflammation 尾崎　貴士、神山　長慶、Benjawan Saechue、曽我　泰裕、後藤　亮、仲山 達也、福田　千瑛、Astri Dewayani、Thanyakorn Chalalai、有木　晋平、小坂　聡太郎、園田　光、広瀬　晴奈、玄同　淑子、野口　香緒里、佐知　望美、飛彈野　真也、前島　圭佑、後藤　孔郎、正木　孝幸、石井　宏治、長田　良雄、柴田　洋孝、小林　隆志 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12944

Brief Report

Pages: 505-511 キイロショウジョウバエmago nashi変異体にみられる変異をもつMagohタンパク質はエクソン接合部複合体への組み込みが低下する Mutations equivalent to Drosophila mago nashi mutants imply reduction of Magoh protein incorporation into exon junction complex 押月　紗矢、松本　英里、田中　智、片岡　直行 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12941