Vol. 27, No. 5(May 2022)

Numerous rafts and small boats float in the river, which flows in the shape of a cup, surrounding a pond with an islet. They look as if they are part of the cells of the green alga Chlamydomonas. In the chloroplasts surrounding the nucleus, thylakoids overlap each other to form the grana. The long rafts in particular look like lamellae interconnecting the grana. The central sandbar with the rafts moored to it resemble a pyrenoid (a structure found in the chloroplasts of algae) with thylakoid membranes penetrating the pyrenoid itself. We referred to Figure 1(A) of Engel et al. (2015) eLife 4:e04889, DOI: 10.7554/eLife.04889.001. We would like to thank Dr. Takashi Yamano (Graduate School of Biostudies, Kyoto University) for his advice.

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Genes to Cells © 2022 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 27, Issue 5, 2022.

Original Articles

Pages: 317-330 細胞質アクチン-EGFPを発現するU2OS細胞におけるファロイジン非染色性核内アクチン線維の機能解析 Characterization of phalloidin-negative nuclear actin filaments in U2OS cells expressing cytoplasmic actin-EGFP 長崎　晃、加藤　薫、星　柾充、戸井　基道、中村　史、上田　太郎 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12930

Pages: 331-344 XRCC1遺伝子の欠損が、PARP阻害剤の治療効果をなぜ大きく上昇するか、その機序を解明した XRCC1 counteracts poly(ADP ribose)polymerase (PARP) poisons, olaparib and talazoparib, and a clinical alkylating agent, temozolomide, by promoting the removal of trapped PARP1 from broken DNA 廣田　耕志、大岡　正人、清水　直登、山田　航世、津田　雅貴、Mahmoud Abdelghany Ibrahim、山田　真太郎、笹沼　博之、益谷　美都子、武田　俊一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12929

Pages: 345-355 脳に高発現するオーファン受容体であるGPR85の新規リガンド開発 Development of novel potent ligands for GPR85, an orphan G protein-coupled receptor expressed in the brain 酒井　彩、安井　猛、渡邊　将、巽　理寧、山本　芳彦、高野　亘、谷　祐毅、岡村　和泉、平井　宏和、武田　茂樹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12931

Pages: 356-367 DNA修復因子XPF-ERCC1エンドヌクレアーゼの核局在に関与する領域の同定 Mapping of the regions implicated in nuclear localization of multi-functional DNA repair endonuclease XPF-ERCC1 赤堀　稜、高森　千枝、若杉　光生、松永　司 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12932

Brief Report

Pages: 368-375 間葉系幹細胞を起点とする細胞自律的および細胞間ケモカインシグナルが未分化型胃がん細胞の移動能を制御する Autonomous and intercellular chemokine signaling elicited from mesenchymal stem cells regulates migration of undifferentiated gastric cancer cells 岡本　大輝、山内　菜津子、瀧口　豪介、西田　満、掛地　吉弘、南　康博、紙崎　孝基 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12933