Vol. 24, No. 9(September 2019)

A cluster of butterflies with eyespots on their wings fly away in the sky with concentric circles. Looking carefully, they consist of individuals with wild-type eyespots and mutants with different patterns than the wild-type. There are various theories about the mechanism of forming eyespots. One of them is that it involves the concentric diffusion of a morphogen from the center, but it has recently begun to be questioned. We thank Dr. Shigeyuki Koshikawa (Graduate School of Environmental Science, Hokkaido University) for providing us an idea of drawing and the current status of research in this field.

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Genes to Cells © 2019 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 24, Issue 9, 2019.

Original Article

Pages: 596-607 インテグリンα6のアミノ酸配列解析によるbasal-like乳癌の転移抑制のための標的残基の同定 In silico analysis-based identification of the target residue of integrin α6 for metastasis inhibition of basal-like breast cancer 田中　直、仙田　典子、飯田　敦夫、瀬原　淳子、石井　智子、佐藤　史顕、戸井　雅和、伊東　潤二 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12714

Brief Reports

Pages: 608-618 出芽酵母ORCは特異的塩基性パッチに依存して１本鎖DNA上で重合しATP加水分解を促進する Specific basic patch-dependent multimerization of Saccharomyces cerevisiae ORC on single-stranded DNA promotes ATP hydrolysis 川上　広宣、村岡　龍哉、大橋　英治、川畑　健太、金本　祥太、千々布　壮陽、釣本　敏樹、片山　勉 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12710

Pages: 619-626 C/EBPδの欠損は腸管上皮細胞のアポトーシスを促進しマウスにおける実験的大腸炎を悪化させる Loss of C/EBPδ enhances apoptosis of intestinal epithelial cells and exacerbates experimental colitis in mice 如澤　浩樹、山内（井上）　茜、有村　純暢、山梨　裕司 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12711

Pages: 627-635 ストレス誘導性で、ATF7依存的なエピジェネティック変化は細胞老化に影響する Stress-induced and ATF7-dependent epigenetic change influences cellular senescence 前川　利男、Binbin Liu、Yang Liu、吉田　圭介、村谷　匡史、Bruno Chatton、石井　俊輔 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12713