Vol. 23, No. 5(May 2018)

This is an acrobatic performance imitating immunoprecipitation using a phosphorylated protein-specific antibody. Two boys are acting two forms of a substrate protein. The boy on the left who wears red trousers, that represent the phosphorylation site of the substrate protein, is showing an opened fan and striking a pose that looks like the active form of the substrate protein. The other one who wears blue trousers is squatting on the ground to play the role of the dephosphorylated, inactive form of the substrate protein. The man who is suspended upside down in the midair is acting a phospho-specific antibody, and grasping the red trousers only, i.e. the site of phosphorylation.

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Genes to Cells © 2018 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 23, Issue 5, 2018.

Original Articles

Pages: 332-344 哺乳類無細胞系において非アデニル化mRNAの翻訳をmicroRNPが活性化する MicroRNP-mediated translational activation of non-adenylated mRNAs in a mammalian cell-free system 脇山　素明、尾上　耕一、岩岡　諒、青木　一真、星野　真一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12580

Pages: 345-356 Dullard遺伝子欠損は、成体卵胞に出血を引き起こす Dullard deficiency causes hemorrhage in the adult ovarian follicles 早田　匡芳、値賀　正彦、江面　陽一、浅島　誠、片渕　秀隆、西中村　隆一、野田　政樹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12575

Pages: 357-369 The role of ω-subunit of Escherichia coli RNA polymerase in stress response Neerupma Bhardwaj, Kirtimaan Syal and Dipankar Chatterji https://onlinelibrary.wiley.com/doi/10.1111/gtc.12577

Pages: 370-385 αカテニンの張力感知領域は自己阻害構造で見られる分子内相互作用による安定化が失われると天然変性領域となる The force-sensing device region of α-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form 平野　良憲、天野　優、米村　重信、箱嶋　敏雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12578

Brief Reports

Pages: 386-392 Nrf2の過剰な活性化は骨形成低下を引き起こす Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo 吉田　瑛紀、鈴木　隆史、守田　匡伸、田口　恵子、土田　恒平、本橋　ほづみ、土井田　稔、山本　雅之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12579

Pages: 393-399 ヒト末梢概日時計の調節におけるインスリンの関与 Potential role of the pancreatic hormone insulin in resetting human peripheral clocks 梶本　潤、松村　律子、野出　孝一、明石　真 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12582