Vol. 23, No. 2(February 2018)

節分の枡と豆で表す細胞内部のジャングル
In Japan, people cerebrate Setsubun, the day before the lunar calendrical beginning of spring, around 3rd of February every year. People decorate sardine heads and holly leaves, put soy beans in a square wooden measuring box ('masu'), and scatter the beans to expel the bad spirits. Putting not only ordinary soybeans, but also other kinds of beans, we expressed a scene of the inside of a cell in the masu just like a bonsai. The real inside of the cells isn't sparse, but very much crowded, like this masu, with cellular organelles such as the nucleus, mitochondria, secretory vesicles and Golgi apparatus and cytoskeletons as well. For drawing this image, we referred to an essay by Shoichiro Tsukita https://www.brh.co.jp/seimeishi/journal/009/ss_4.html.

Genes to Cells © 2018 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 23, Issue 2, 2018.

Original Articles

Pages: 60-69 インビボリプログラミングによるマウス腎腫瘍における概日時計の破綻機構 Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors 大橋 宗洋、梅村 康浩、小池 宣也、土谷 佳樹、稲田 裕、渡邊 仁美、田中 智子、南 陽一、浮村 理、三木 恒治、田尻 達郎、近藤 玄、山田 泰広、八木田 和弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12552

Pages: 70-79 蛋白質の凝集を抑制する化合物を効率よく見つける:標的蛋白質の末端欠失変異体を利用する溶液スクリーニング Efficient identification of compounds suppressing protein precipitation via solvent screening using serial deletion mutants of the target protein 柚木 芳、吉永 壮佐、武田 光広、長野 良平、土屋 祐輔、薗田 晃弘、辻 辰一朗、平金 真、遠田 悦子、寺島 裕也、松島 綱治、寺沢 宏明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12554

Pages: 80-93 ショウジョウバエの生体老化に影響を与えるmiR-305とその標的遺伝子の同定 Identification of miR-305, a microRNA that promotes ageing, and its target mRNAs in Drosophila 上田 真貴子、佐藤 哲也、大川 恭行、井上 喜博 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12555

Pages: 94-104 G0核ではDDKのpre-RCへの結合が抑制されている Suppression of targeting of Dbf4-dependent kinase to pre-replicative complex in G0 nuclei 岡田 拓也、岡部 岳、卓 妍秀、三村 覚、滝澤 温彦、久保田 弓子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12556

Brief Reports

Pages: 105-111 植物一過性発現系による核局在性RNAの可視化 Visualizing nuclear localized RNA using transient expression system in plants 木下 奈都子、Catalina Arenas-Huertero、Nam-Hai Chua https://onlinelibrary.wiley.com/doi/10.1111/gtc.12549

Pages: 112-116 誘導性制御性T細胞分化に対するneuraminidase 3の役割 Contribution of neuraminidase 3 to the differentiation of induced regulatory T cells 神沼 修、加藤 茂樹、宮城 妙子、渡邊 伸昌、北村 紀子、西村 友枝、佐伯 真弓、森 晶夫、廣井 隆親 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12553