Vol. 22, No. 4(April 2017)

Today, more than one fourth of people living in Japan are estimated to be suffering from 'sugi' or Japanese cedar (Cryptomeria japonica) pollinosis. Spring should be the worst season for those with such allergies. Binding of the allergen to immunoglobulin E (IgE) on the surface of mast cells triggers release of histamine from them, and it causes symptoms such as itchy eyes or snivel. However, it's not a problem only for human beings. This monkey performing saru-mawashi (monkey show) also has a pollen allergy, and today's stage is, of all places, beside the very sugi tree!

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Genes to Cells © 2017 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 22, Issue 4, 2017.

Original Articles

Pages: 334-347 TAF-Iはサブタイプ依存的な分子内相互作用を介して自身のヒストンH1シャペロン活性を制御する Histone H1 chaperone activity of TAF-I is regulated by its subtype-dependent intramolecular interaction 鍛谷　香織、加藤　広介、永田　恭介 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12478

Pages: 348-359 ジストログリカノパチー原因遺伝子産物POMKの立体構造解析 3D structural analysis of protein O-mannosyl kinase, POMK, a causative gene product of dystroglycanopathy 長江　雅倫、Sushil K. Mishra、根谷崎　牧子、大井　里香、池田　明美、松垣　直宏、明石　知子、萬谷　博、水野　真盛、矢木　宏和、加藤　晃一、千田　俊哉、遠藤　玉夫、禾　晃和、山口　芳樹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12480

Pages: 360-375 マウスES細胞でGemininはCdt1阻害分子として必須である Geminin is an indispensable inhibitor of Cdt1 in mouse embryonic stem cells 細金　正樹、Lena Bosu、福本　恵美子、山田　秀俊、佐藤　聡一郎、中山　啓子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12482

Pages: 376-391 核アクチン繊維によるクロマチンの核膜への繋留：ツメガエル胞胚におけるアクチン細胞骨格の新たな役割 Chromatin tethering to the nuclear envelope by nuclear actin filaments: a novel role of the actin cytoskeleton in the Xenopus blastula 小田　春佳、白井　菜月、浦　菜緒子、大隅　圭太、岩渕　万里 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12483

Pages: 392-405 チミンDNAグリコシラーゼは塩基除去修復依存的及び非依存的にDNA損傷応答と遺伝子発現を制御する Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms 中村　知史、村上　浩一、多田　遥人、上原　芳彦、野上　順平、前原　一満、大川　恭行、斉藤　寿仁、西谷　秀男、小野　哲也、西　良太郎、横井　雅幸、酒井　恒、菅澤　薫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12481

Pages: 406-417 Dickkopf 3 (DKK3) はxanthine dehydrogenase (XDH) 発現を抑制し酸化ストレスによるアポトーシスを防御する Dickkopf 3 attenuates xanthine dehydrogenase expression to prevent oxidative stress-induced apoptosis 邱　爽、加野　准子、野口　雅之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12484