Vol. 21, No. 8(August 2016)

An infant and his mother are playing with a small fish in a tub. The tub has a knothole from which water is pouring out, so the infant is carefully holding the small fish not to let it out from the hole. In the plasma membrane in various species, from bacteria to higher eukaryotes, there are such water channels called aquaporins that selectively allow water molecules to traverse the membrane. The schematized secondary and tertiary structures of the aquaporin's monomer are drawn on his mother's kimono and sash, respectively. And, aquaporins form tetramers to function in the plasma membrane just like the pattern drawn on the infant's kimono.

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Genes to Cells © 2016 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 21, Issue 8, 2016.

Original Articles

Pages: 812-832 核内膜タンパク質 Lem2によるヘテロクロマチンの増強は栄養条件に依存して起こる Inner nuclear membrane protein Lem2 augments heterochromatin formation in response to nutritional conditions 丹下　喜恵、近重　裕次、高畑　信也、川上　慶、東　傑人、森　知栄、糀谷　知子、平野　泰弘、淺川　東彦、村上　洋太、原口　徳子、平岡　泰 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12385

Pages: 833-851 Cyclophilin PpiB is involved in motility and biofilm formation via its functional association with certain proteins Aggeliki Skagia, Chrysoula Zografou, Eleni Vezyri, Anastasia Venieraki, Panagiotis Katinakis and Maria Dimou https://onlinelibrary.wiley.com/doi/10.1111/gtc.12383

Pages: 852-860 滑膜肉腫細胞株はDNA修復活性が低下し、PARP阻害剤に感受性を示す Synovial sarcoma cell lines showed reduced DNA repair activity and sensitivity to a PARP inhibitor 山崎　寛之、大野（宮本）　麻美子、山本　悠貴、近藤　格、渡邉　俊樹、太田　力 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12387

Pages: 861-873 蛍光観察によるシャペロン介在性オートファジーとミクロオートファジーの活性評価 Fluorescent-based evaluation of chaperone-mediated autophagy and microautophagy activities in cultured cells 佐藤　正寛、関　貴弘、今野　歩、平井　宏和、倉内　祐樹、久恒　昭哲、香月　博志 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12390

Pages: 874-889 M期キナーゼNEK6によるヒトテロメレース・テロメア長制御 NEK6-mediated phosphorylation of human TPP1 regulates telomere length through telomerase recruitment 平井　悠吾、田村　美樹、大谷　淳二、石川　冬木 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12391

Pages: 890-900 KaiABC時計振動子試験管内再構成系におけるKaiA-KaiC複合体形成とKaiB-KaiC複合体形成の概日リズム Circadian oscillations of KaiA-KaiC and KaiB-KaiC complex formations in an in vitro reconstituted KaiABC clock oscillator 村上　怜子、武藤　梨沙、石井　健太郎、石浦　正寛 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12392

Brief Reports

Pages: 901-906 新規ゴルジ阻害薬M-COPAは、腸管出血性大腸菌の産生する志賀毒素によるアポトーシスを抑制する M-COPA, a novel Golgi system disruptor, suppresses apoptosis induced by Shiga toxin 服部　隆行、高橋　美帆、椎名　勇、大橋　愛美、旦　慎吾、西川　喜代孝、矢守　隆夫、内藤　幹彦 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12386

Pages: 907-914 大腸菌の複製フォーク進行はDNA複製オリジン近傍の二つの大きな染色体領域で一時停止する Replication fork progression is paused in two large chromosomal zones flanking the DNA replication origin in Escherichia coli 秋山　昌広、大島　拓、Onuma Chumsakul、石川　周、真木　寿治 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12388

Pages: 915-920 ID2によるヒト唾液腺癌細胞における悪性形質の制御 Targeting ID2 expression triggers a more differentiated phenotype and reduces aggressiveness in human salivary gland cancer cells 住田　知樹、石川　詔子、中野　旬之、山田　朋弘、森　悦秀、Pierre-Yves Desprez https://onlinelibrary.wiley.com/doi/10.1111/gtc.12389

Pages: 921-929 cAMPおよびCa²⁺シグナルのバランスが神経細胞におけるPACAP遺伝子発現レベルを制御する Balance between cAMP and Ca²⁺ signals regulates expression levels of pituitary adenylate cyclase-activating polypeptide gene in neurons 福地　守、桑名　由紀、田渕　明子、津田　正明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12393