Vol. 21, No. 5(May 2016)

Flow cytometry is a technology that allows high throughput analysis of the characteristics of cell populations by optically and rapidly measuring the morphological characteristics and fluorescent signals of the cells suspended in a narrow stream of fluid in equipment (flow cytometer). In addition, the equipment with a cell sorter can collect a certain type of cells from a heterogeneous population by charging droplets containing such cells identified by the optical data and attracting them by an electrostatic deflector. In this post town in this drawing, 'Positive' inn on the right and 'Negative' inn on the left are finding and attracting potential customers from passersby. They just look like a cell sorter. There is seen above them a cluster of clouds that resembles flow cytometric data.

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Genes to Cells © 2016 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 21, Issue 5, 2016.

Meeting Report

Pages: 392-395 トランスポゾン転移とゲノム編集技術に関する国際会議２０１５のレポート： 古都奈良で紹介された最先端ゲノム改変技術 Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara ウォルツェン　クヌート、山本　卓、國府　力、竹田　潤二 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12367

Original Articles

Pages: 396-407 ヒトSNPsの分布はべき乗則で近似され、フラクタル構造を示す Distribution of human single nucleotide polymorphisms is approximated by the power law and represents a fractal structure 合田　徳夫、志波　優、明石　基洋、吉川　博文、笠原　堅、古澤　満 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12344

Pages: 408-424 異なるタイプのタンパク質分解システムがミトコンドリアの融合・分裂バランスによる形態の恒常性制御に関与する Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission 細田　將太郎、石原　孝也、前田　真希、家村　俊一郎、夏目　徹、三原　勝芳、石原　直忠 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12351

Pages: 425-441 Mib1はSnx18を介したdynamin 2の局在化を制御しDll1のエンドサイトーシスを促進してNotchシグナル活性化に寄与する Mib1 modulates dynamin 2 recruitment via Snx18 to promote Dll1 endocytosis for efficient Notch signaling 岡野　誠、松尾　宏美、西村　侑也、穂積　勝人、吉岡　佐保、殿城　亜矢子、伊藤　素行 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12350

Pages: 442-456 ショウジョウバエの器官特異性の決定に関わるWGEはhistone locus bodyに局在し、ヒストン遺伝子の発現を制御することでゲノム安定性に関わる Organ identity specification factor WGE localizes to the histone locus body and regulates histone expression to ensure genomic stability in Drosophila 小澤　奈央、古橋　寛史、増子　恵太、沼尾　恵利子、牧野　能士、矢野　環、倉田　祥一朗 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12354

Pages: 457-465 GRP78はホスファチジルイノシトール3リン酸（PIP3）脱リン酸化酵素SKIPと直接結合して、SKIPの細胞内局在を決定する Glucose-regulated protein 78 (GRP78) binds directly to PIP₃ phosphatase SKIP and determines its localization 伊集院　壮、波多野　直哉、竹縄　忠臣 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12353

Pages: 466-481 TDP-43はmRNAのグアニン四重鎖構造と結合し局所翻訳のための輸送を担っている TDP-43 binds and transports G-quadruplex-containing mRNAs into neurites for local translation 石黒　亮、木村　展之、渡邊　裕斗、渡邉　すみ子、石浜　明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12352

Pages: 482-491 Ctf18-RFCとDNA polymerase ε 間の相互作用は生物種を越えて高度に保存されており、出芽酵母ではゲノム安定性の維持に重要である Conserved interaction of Ctf18-RFC with DNA polymerase ε is critical for maintenance of genome stability in Saccharomyces cerevisiae 沖本　寛子、田中　誠司、荒木　弘之、大橋　英治、釣本　敏樹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12356

Pages: 492-504 ゼブラフィッシュ脳下垂体細胞分化における時間的なNotchシグナルの働きとその下流因子との関連性に関する解析 Temporal effects of Notch signaling and potential cooperation with multiple downstream effectors on adenohypophysis cell specification in zebrafish 中原　良成、武藤　彰彦、平林　諒、佐久間　哲史、山本　卓、粂　昭苑、菊池　裕 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12358

Pages: 505-516 ビブリオ菌べん毛固定子タンパク質PomBのペリプラズム領域変異が起こすモーター機能障害のセリンによる抑圧 Serine suppresses the motor function of a periplasmic PomB mutation in the Vibrio flagella stator 錦野　達郎、朱　世偉、竹川　宜宏、小嶋　誠司、尾上　靖宏、本間　道夫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12357

Brief Report

Pages: 517-524 FBXL12は細胞自律的にT細胞分化を制御する FBXL12 regulates T-cell differentiation in a cell-autonomous manner 仁田　暁大、西山　正章、武藤　義治、中山　敬一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12360