Vol. 20, No. 11(November 2015)

The normal white (w⁺) gene in Drosophila is required for production of red pigment in the eyes. In some mutants in which the w⁺ gene has been moved to a region near the centrosomal heterochromatin due to an inversion in the X chromosome, the eyes are mottled with red and white patches; the w⁺ gene in the white cells has been silenced due to spreading heterochromatin, while w⁺ gene in the red cells is active. This phenomenon is called PEV (position-effect variegation), and a number of factors that control epigenetics, such as histone methyltransferases, have been identified by measuring the extent of variegation. Now, in this sliding screen, maple leaves in autumn were drawn with Japanese ink on gold foil background except some in the central oval with a red paint as an accent. A shadow that looks like Drosophila happened to be cast on it, emerging a figure of the w mutant with a mottled eye.

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Genes to Cells © 2015 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 20, Issue 11, 2015.

Original Articles

Pages: 871-886 膵ベータ細胞におけるリン酸化eIF2α依存的翻訳抑制の解除およびインスリン生合成へのGADD34とCRePの恒常的役割 Constitutive role of GADD34 and CReP in cancellation of phospho-eIF2α-dependent translational attenuation and insulin biosynthesis in pancreatic β cells 赤井　良子、細田　章、吉野　麻由子、岩脇　隆夫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12279

Pages: 887-901 レトロトランスポゾン挿入配列とノンコーディングRNA 4.5SHを介した遺伝子発現制御 Regulation of gene expression via retrotransposon insertions and the noncoding RNA 4.5S RNA_H 石田　賢太郎、宮内　健常、木村　優子、水戸　麻理、岡田　俊平、鈴木　勉、中川　真一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12280

Pages: 902-914 ショウジョウバエ胚発生過程におけるヒストンメチル基転移酵素dG9a標的遺伝子のゲノムワイド同定 Genomewide identification of target genes of histone methyltransferase dG9a during Drosophila embryogenesis 嶋路　耕平、小西　貴大、田中　伸太朗、吉田　英樹、加藤　容子、大川　恭行、佐藤　哲也、須山　幹太、木村　宏、山口　政光 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12281

Pages: 915-931 大腸菌二成分制御系転写因子OmpRの制御機能の拡大：SELEX法による新規制御標的の探索 Expanded roles of two-component response regulator OmpR in Escherichia coli: genomic SELEX search for novel regulation targets 島田　友裕、高田　啓、山本　兼由、石浜　明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12282

Pages: 932-942 C. elegansの始原生殖細胞に限局するmrg-1 mRNAの分布パターンは、生殖顆粒非依存的な安定性制御により生まれる Restricted distribution of mrg-1 mRNA in C. elegans primordial germ cells through germ granule-independent regulation 巳波　孝至、高崎　輝恒、井上　邦夫、坂本　博 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12285

Pages: 943-955 高温適応進化における制御と品質管理の機能特化 Functional specialization in regulation and quality control in thermal adaptive evolution 山　和馬、松本　悠希、村上　由衣、瀬尾　茂人、松田　秀雄、後藤　和義、元岡　大祐、中村　昇太、應　蓓文（イン　ベイウェン）、四方　哲也 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12298

Brief Report

Pages: 956-965 大腸菌内膜タンパク質YciBは、細胞分裂に重要なタンパク質ZipAに作用する Escherichia coli inner membrane protein YciB interacts with ZipA that is important for cell division Noor Afiza Badaluddin、北川　円 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12299