Vol. 20, No. 7(July 2015)

ヒストンの笹にエピジェネティックな飾り付け
One of the highlights of the month of July in Japan is Tanabata (Star Festival). Tanabata, a festival to pray to the stars in the Milky Way in summer, was imported from ancient China. People in Edo era started to decorate bamboo branches with ‘tanzaku’ (small pieces of paper) on which they wrote their wishes, and to pray the wishes would come true. The bamboo branches in this drawing are likened to histone tails (H2A, H2B, H4 and H3 from the left). The tanzakus represent epigenetic modifications (acetylation, methylation and phosphorylation) of amino acid residues in histone tails. If you use this histone bamboo, mind that you have to phrase your wishes with the types, positions and combinations of decorations (or modifications). You need a textbook to perform modifications correctly.

Genes to Cells © 2015 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 20, Issue 7, 2015.

Review Article

Pages: 543-562 タンパク質モノユビキチン化:基質と機能 Protein monoubiquitylation: targets and diverse functions 中川 直、中山 啓子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12250

Original Articles

Pages: 563-577 新規NRF1タンパク質モニタリングシステムによる化合物ライブラリスクリーニングから創出されたNRF1に特異的な活性化化合物 Discovery of an NRF1-specific inducer from a large-scale chemical library using a direct NRF1-protein monitoring system 辻田 忠志、Liam Baird、古澤 祐樹、勝岡 史城、彭 よしか、後藤 智美、川口 真一、山本 雅之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12248

Pages: 578-589 腸内常在菌によるcarcinoembryonic antigen-related cell adhesion moleculeの腸上皮における発現制御 Regulation by gut commensal bacteria of carcinoembryonic antigen-related cell adhesion molecule expression in the intestinal epithelium 北村 泰明、村田 陽二、朴 貞河、小谷 武徳、今田 慎也、齊藤 泰之、岡澤 秀樹、東 健、的崎 尚 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12247

Pages: 590-600 ゼブラフィッシュ・ヘムオキシゲナーゼ1のNrf2依存的発現誘導は、ヘムとBach1の作用により肝臓特異的かつ一過的になる Heme-mediated inhibition of Bach1 regulates the liver specificity and transience of the Nrf2-dependent induction of zebrafish heme oxygenase 1 布施 雄士、中島 瞳、中島 やえ子、中島 修、小林 麻己人 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12249

Pages: 601-612 大腸菌二成分制御系のNarLファミリーレスポンスレギュレーター間におけるクロストーク Cross talk in promoter recognition between six NarL-family response regulators of Escherichia coli two-component system 吉多 美祐、石浜 明、山本 兼由 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12251

Pages: 613-624 二種の翻訳伸長因子を23S rRNAのsarcin/ricin loopにリクルートする古細菌リボソームストーク蛋白質C末端部の役割 Functional role of the C-terminal tail of the archaeal ribosomal stalk in recruitment of two elongation factors to the sarcin/ricin loop of 23S rRNA 今井 大達、三好 智博、村上 僚、伊東 孝祐、石野 良純、内海 利男 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12256