Vol. 19, No. 7(July 2014)

A scene of Yuzen Nagashi (a process of washing kimono silks) at a pontoon bridge over a river. This bridge actually illustrates the way a number of ribosomes (boats) are attached in a row along a single mRNA chain (a bridge) to translate in parallel, and then form a polysome. There is a grove, which is like a poly-A tail, extending from the bridge to the opposite bank of the river. The pieces of fabric form polypeptide chains synthesized by ribosomes with their edges trimmed in the shape of 'M' that is the abbreviation of methionine. Now, the translation processes probably have just terminated at the boats on the far end. The fabric is being folded while it is released from those boats.

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Genes to Cells © 2014 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 19, Issue 7, 2014.

Original Articles

Pages: 541-554 分裂酵母セントロメアタンパク質Mis19はMis16とMis18を繋ぎ、NMD因子およびSWI/SNF複合体との相互作用を介してCENP-Aをリクルートする Schizosaccharomyces pombe centromere protein Mis19 links Mis16 and Mis18 to recruit CENP-A through interacting with NMD factors and the SWI/SNF complex 林　武志、江部　正弘、長尾　恒治、國分　綾、佐二木　健一、柳田　充弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12152

Pages: 555-564 ゼブラフィッシュにおけるCRISPR/Cas9システムを用いた多重遺伝子破壊 Multiple genome modifications by the CRISPR/Cas9 system in zebrafish 太田　聡、久野　悠、井川　善也、川原　敦雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12154

Pages: 565-581 JNK1/2依存的なangulin-1/LSRのリン酸化は、EpH4上皮細胞シートの三細胞接着点への、angulin-1/LSRとtricellulinの局在化に必須である JNK1/2-dependent phosphorylation of angulin-1/LSR is required for the exclusive localization of angulin-1/LSR and tricellulin at tricellular contacts in EpH4 epithelial sheet 中津　大貴、加納　ふみ、田口　由起、菅原　太一、西園　貴志、西川　喜代孝、小田　裕香子、古瀬　幹夫、村田　昌之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12158

Pages: 582-593 メディエーターMED18サブユニットはCDK/サイクリンモジュールを介して転写を負に制御している Mediator MED18 subunit plays a negative role in transcription via the CDK/cyclin module 熊藤　将之、梅村　啓靖、古元　義、深澤　力也、田中　亜紀、大熊　芳明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12155

Pages: 594-601 Identification of two functional PCNA-binding domains in human DNA polymerase κ Jung-Hoon Yoon, Narottam Acharya, Jeseong Park, Debashree Basu, Satya Prakash and Louise Prakash https://onlinelibrary.wiley.com/doi/10.1111/gtc.12156