Vol. 19, No. 5(May 2014)

Two artisans are heaping up lumber in the form of layers. The process where the lumber is going to be piled up perfectly in six horizontal layers reminds us of the cerebral cortex in corticogenesis. One of the artisans below, on whose back a Chinese character ‘kan’ (‘stem’) can be seen, may play the role of the neural stem cell (radial glia cell), the source of new lumbers (newly created neurons), and extends a rope (radial glia fibers) upward so as to carry the lumber properly to the top layer. The other artisan above is considered to play a role similar to the cells that secrete reelin. The reelin is a protein that regulates correct migration and positioning of neurons.

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Genes to Cells © 2014 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 19, Issue 5, 2014.

Original Articles

Pages: 359-373 染色体接着部位にみられる組換えコールドスポット Meiotic recombination cold spots in chromosomal cohesion sites 伊藤　将、久郷　和人、Jeffrey A. Fawcett、村　幸子、池田　晶、印南　秀樹、太田　邦史 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12138

Pages: 374-385 Dkk1によるWntシグナルの抑制が5′エンハンサーを介してHesx1の発現を活性化するとともに前脳前駆体の発生を促す Dkk1-dependent inhibition of Wnt signaling activates Hesx1 expression through its 5′ enhancer and directs forebrain precursor development 松田　一成、近藤　寿人 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12136

Pages: 386-404 高親和性受容体PYL9/RCAR1の構造から明らかになった会合状態非依存的なアブシジン酸認識機構 Mechanism of high-affinity abscisic acid binding to PYL9/RCAR1 中川　雅啓、賀儀山　めぐみ、柴田　展行、平野　良憲、箱嶋　敏雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12140

Pages: 405-418 細胞分裂制御因子SdiAによるQSシグナルの感知と転写調節標的の変換 Roles of cell division control factor SdiA: recognition of quorum sensing signals and modulation of transcription regulation targets 島田　友裕、島田　佳織、松井　誠、鍛代　悠一、五十嵐　潤、菅　裕明、石浜　明 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12139

Pages: 419-431 TALENによって突然変異や大きな欠失を誘導された細胞を濃縮するためのFAST-idシステム FAST-id system for enrichment of cells with TALEN-induced mutations and large deletions 徳増　大輔、佐久間　哲史、林　陽子、細井　紗弥佳、檜山　英三、山本　卓 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12142

Pages: 432-440 漢方薬・人参養栄湯はin vitroにおいて赤血球系造血ではなく骨髄球系造血を促進する Herbal drug ninjin'yoeito accelerates myelopoiesis but not erythropoiesis in vitro 井上　朋子、Kasem Kulkeaw、Kanitta Muennu、田中　由香、中西　洋一、杉山　大介 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12143

Pages: 441-448 哺乳類サーカディアン行動リズムの同調におけるP53の役割 Role of p53 in the entrainment of mammalian circadian behavior rhythms 浜田　俊幸、仁木　朋子、石田　直理雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12144