Vol. 19, No. 3(March 2014)

FRET (Fluorescence Resonance Energy Transfer), which is a phenomenon of energy transfer between two adjacent fluorescent molecules, has been applied to visualization of interaction between proteins in living cells and so on. To carry out high-efficiency FRET, not only the distance between two molecules must be very close (less than about 10 nm) but the relative orientation of two chromophores must also be optimized. One of the women in this picture carries the other with attention paid on how they are oriented to each other, and successfully lightens the plum blossoms just like FRET.

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Genes to Cells © 2014 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 19, Issue 3, 2014.

Original Articles

Pages: 177-197 低分子量Gタンパク質Rabを介するメンブレントラフィックとPI4,5P₂シグナルの機能的関係 Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P₂ signaling 李　翠芳、喜多　綾子、橋本　佑香、井原　美沙子、加藤　彩香、小倉　尚也、土井　章、奥　公秀、伊藤　俊樹、阪井　康能、杉浦　麗子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12123

Pages: 198-208 転写因子セットによるヒト網膜視細胞への分化誘導 Derivation of human differential photoreceptor cells from adult human dermal fibroblasts by defined combinations of CRX, RAX, OTX2 and NEUROD 世古　裕子、東　範行、石井　俊行、小牟田　縁、宮本　潔子、宮川　世志幸、金田　誠、梅澤　明弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12127

Pages: 209-224 プロテアソームの異常調節はALS関連変異型SOD1の毒性を増加させる Dysregulation of the proteasome increases the toxicity of ALS-linked mutant SOD1 北村　朗、稲田　のりこ、久保田　広志、松本　弦、金城　政孝、Richard I. Morimoto、永田　和宏 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12125

Pages: 225-238 RNA結合タンパク質のSpo5はサイクリンCdc13を制御して分裂酵母の減数第二分裂を進行させる The RNA-binding protein Spo5 promotes meiosis II by regulating cyclin Cdc13 in fission yeast 新　真由美、佐藤　政充、山下　朗、山本　正幸 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12133

Pages: 239-253 Keap1-Nrf2制御系は造血幹細胞の分化を制御する Keap1-Nrf2 system regulates cell fate determination of hematopoietic stem cells 村上　昌平、清水　律子、Paul-Henri Romeo、山本　雅之、本橋　ほづみ https://onlinelibrary.wiley.com/doi/10.1111/gtc.12126

Pages: 254-272 脱ユビキチン化酵素CYLD, OTULINはLUBACとの結合を介して、LUBACの直鎖状ポリユビキチン鎖生成を抑制する Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN 瀧内　剛、中川　朋子、田宮　大也、藤田　宏明、佐々木　義輝、佐伯　泰、竹田　浩之、澤崎　達也、Alexander Buchberger、木村　正、岩井　一宏 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12128