Vol. 18, No. 9(September 2013)

Tadataka Inou (1745-1818) was over 50 when he retired from the family business and started to learn Western astronomy. At the age of 55, he led a surveying team to travel throughout Japan islands (40,000 kilometers in total) spending 17 years, and accomplished the first Japanese actual measured map, Dai Nihon Enkai Yochi Zenzu, based on the data collected during the survey. The map created about 200 years ago was so accurate that it later amazed the western surveying teams visiting the country. This month's cover art illustrates Tadataka Inou and his team working together to accomplish a metabolic map. Inspired by Figure 2-35 in The Molecular Biology of the Cell, 5th ed. (Alberts et al. 2008).

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Genes to Cells © 2013 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 18, Issue 9, 2013.

Original Articles

Pages: 723-732 大腸菌複製再開始複合体構成因子PriCのドメイン化による機能解析 Domain separation and characterization of PriC, a replication restart primosome factor in Escherichia coli 荒牧　峻彦、阿部　義人、大栗　誉敏、三島　朋徳、山下　昭二、片山　勉、植田　正 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12069

Pages: 733-752 APC/サイクロソームを介した核膜動態の制御は、ジャポニカス分裂酵母でみられる半開放型分裂期の進行に必要である Regulation of nuclear envelope dynamics via APC/C is necessary for the progression of semi-open mitosis in Schizosaccharomyces japonicus 青木　敬太、志波　優、高田　啓、吉川　博文、仁木　宏典 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12072

Pages: 753-763 大腸菌発現系を用いた組換えヒトμ-カルパインの効率的な発現・精製法の確立 Efficient expression and purification of recombinant human μ-calpain using an Escherichia coli expression system 秦　勝志、北村　ふじ子、反町　洋之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12071

Pages: 764-779 複製開始点とorigin recognition complex (ORC)との結合は、ORC・ヌクレオソーム・複製開始点DNAの三者の協調的な相互作用により安定化される Concerted interaction between origin recognition complex (ORC), nucleosomes and replication origin DNA ensures stable ORC-origin binding 日詰　光治、矢倉　勝、荒木　弘之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12073

Pages: 780-797 核小体スキャフォールドタンパク質であるWDR46は、nucleolinおよびDDX21の核小体内の顆粒状部における局在を決定する Nucleolar scaffold protein, WDR46, determines the granular compartmental localization of nucleolin and DDX21 平井　悠哉、Emilie Louvet、小田　俊之、粂田　昌宏、渡邉　祐三、堀米　恒好、竹安　邦夫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12077

Pages: 798-809 クラスター化を伴わない膜脂肪酸飽和化によるIRE1αの活性化 Membrane lipid saturation activates IRE1α without inducing clustering 北井　祐人、有山　博之、河野　望、及川　大輔、岩脇　隆夫、新井　洋由 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12074

Pages: 810-822 Rab13結合蛋白質JRABはfilaminを介して細胞の形態変化を制御する Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins 坂根　亜由子、Ahmed Alamir Mahmoud Abdallah、中野　潔、本田　一文、北村　俊雄、井本　逸勢、松下　夏樹、佐々木　卓也 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12078

Pages: 823-837 SAGAとSLIK複合体の構成因子であるSgf73のC末端は複合体の維持とヘテロクロマチン領域の境界形成に重要である C-terminus of the Sgf73 subunit of SAGA and SLIK is important for retention in the larger complex and for heterochromatin boundary function 釜田　和馬、畑中　彬良、Gayatri Goswami、新名主　カオリ、中山　潤一、浦野　健、畑下　昌範、内田　博之、沖　昌也 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12075