Vol. 19, No. 8(August 2014)

宵の川祭にクラスリン被覆小胞の飾りが映える
Tsushima Tenno Festival has been held every summer in Tsushima city, Aichi prefecture, Japan, for the past 500 years. One of the highlights of the festival is the evening festival called Yoi-matsuri when five boats decorated hemispherically with a lot of illuminated lanterns come down the river. The distinctive shape of the hemispherical decoration reminds us of partially formed clathrin-coated vesicles (CCV). So this summer, we dare to replace the decorations with the one which looks exactly like spherical CCV after completion. On the front side of the river, we place Y-shaped structures modeled on the LDL (low-density lipoproteins) receptor that mediates CCV's capturing LDL. The reflection of the light from the lanterns which represent CCV sparkles on the water surface of the river, and creates a fantastic summer night view.

Genes to Cells © 2014 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 19, Issue 8, 2014.

Original Articles

Pages: 603-619 DDB1-and-Cullin 4-associated Factor 1 (DCAF1) のmerlin/NF2による認識の構造的基礎とDCAF1によるmerlin機能抑制のCD44による阻害による癌化において示唆されること Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function 森 智行、後藤 秀平、白川 麻耶、箱嶋 敏雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12161

Pages: 620-628 Lcn2遺伝子プロモーターのNFκB結合配列の下流にあるDNAエレメントは IκBζとNF-κB p50による転写活性化に必要である DNA element downstream of the κB site in the Lcn2 promoter is required for transcriptional activation by IκBζ and NF-κB p50 神田 朗、山﨑 創、住本 英樹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12162

Pages: 629-636 マウス卵母細胞の成長に伴うDNA 5-ヒドロキシメチルシトシンの挙動 Dynamics of genomic 5-hydroxymethylcytosine during mouse oocyte growth 坂下 陽彦、小林 久人、若生 拓哉、外丸 祐介、秦 健一郎、河野 友宏 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12164

Pages: 637-649 マウス腎臓初期発生におけるレチノイン酸応答遺伝子の同定 Identification and characterization of retinoic acid-responsive genes in mouse kidney development 高山 真美、宮竹 功一、西田 栄介 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12163

Pages: 650-665 転写因子Nrf1(NF-E2-related factor 1)はブドウ糖代謝を障害する Transcription factor NF-E2-related factor 1 impairs glucose metabolism in mice 弘津 陽介、東 知佳、福富 俊明、勝岡 史城、辻田 忠志、柳下 陽子、松山 由香、本橋 ほづみ、宇留野 晃、山本 雅之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12165