Vol. 19, No. 10(October 2014)

コドン表付き台で編むポリペプチド組み紐
This wooden stand called "Marudai" is used for braiding a Kumihimo, a decorative belt used for tying on a kimono sash. This particular Marudai has the top surface engraved with a part of the codon table in order to translate nucleotide sequences of genes into the pattern of Kumihimo (polypeptide chain). The Marudai and bobbins actually play the role of ribosomes and tRNAs that synthesize proteins by translating mRNA sequences into amino acid sequences. The color of threads had changed depending on amino acids. The pattern of Kumihimo being braided in this drawing was obtained from the sequence of human insulin. Nothing can be as cool as gene sequences, which design the pattern of brilliantly colored Kumihimo.

Genes to Cells © 2014 by the Molecular Biology Society of Japan and Wiley Publishing Asia Pty Ltd

Volume 19, Issue 10, 2014.

Original Articles

Pages: 723-742 神経堤特異的Restノックアウトマウスの新生児致死は腸管神経叢の異常による胃腸膨満と関連している Neonatal lethality of neural crest cell-specific Rest knockout mice is associated with gastrointestinal distension caused by aberrations of myenteric plexus 青木 仁美、原 明、大森 良幸、志水 泰武、山田 泰広、國貞 隆弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12172

Pages: 743-754 SUMO化されたタンパクを基質とするユビキチン化酵素、RNF4は、染色体ロスの自然発生を防止する SUMO-targeted ubiquitin ligase RNF4 plays a critical role in preventing chromosome loss 廣田 耕志、津田 雅貴、村井 純子、高木 季代、Islam Shamima Keka、成田 岳雄、藤田 真梨、笹沼 博之、小林 純也、武田 俊一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12173

Pages: 755-765 Transient expression of RAD51 in the late G2-phase is required for cell cycle progression in synchronous Physarum cells Anthony Le Cigne, Vanessa Menil-Philippot, Fabrice Fleury, Masayuki Takahashi and Christophe Thiriet https://onlinelibrary.wiley.com/doi/10.1111/gtc.12174

Pages: 766-777 SIRT2はPGAMの中央ドメインを脱アセチル化し活性抑制する Deacetylation of phosphoglycerate mutase in its distinct central region by SIRT2 down-regulates its enzymatic activity 津坂 剛史、Tingting Guo、矢倉 定一、井上 敏昭、横出 正之、稲垣 暢也、近藤 祥司 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12176

Pages: 778-792 4つのリン脂質ヒドロペルオキシドグルタチオンペルオキシダーゼ遺伝子の欠損は線虫の老化を早める Deletion of the four phospholipid hydroperoxide glutathione peroxidase genes accelerates aging in Caenorhabditis elegans 坂本 太郎、前林 花那、中川 靖一、今井 浩孝 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12175