Vol. 22, No. 6(June 2017)

Fireflies are flying and glowing fantastically. Patterns of firefly squids, 'yakoutake' (glowing mushrooms; Mycena chlorophos) and 'owankurage' (crystal jelly; Aequorea victoria) are seen on kimono. They share a common mechanism in which a class of chemiluminescent substrate (luciferin) is oxidized and excited by the catalytic function of a class of enzymes (luciferase), and light is emitted as a result. There has been a custom of appreciating the glow of fireflies in Japan since ancient times, however, it was possible only for a short period in early summer. Life scientists today are lucky to admire the chemiluminescent signal throughout the year. The structural formulas in the sky, and on the woman's and child's round fans are those of firefly luciferin, its dioxetane derivative and excited oxyluciferin, respectively.

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Genes to Cells © 2017 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 22, Issue 6, 2017.

Original Articles

Pages: 506-520 enChIP-Seq法によるゲノム領域間の物理的相互作用の同定 Identification of physical interactions between genomic regions by enChIP-Seq 藤田　敏次、湯野　美由紀、鈴木　穣、菅野　純夫、藤井　穂高 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12492

Pages: 521-534 TAR RNA/DNA結合タンパク質 43 kDa (TDP-43)のカルボキシル末端断片 (TDP25)に核局在化シグナル配列を付加した時の凝集状態変化 Different aggregation states of a nuclear localization signal-tagged 25-kDa C-terminal fragment of TAR RNA/DNA-binding protein 43 kDa 北村　朗、油野　祥子、武藤　秀樹、金城　政孝 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12495

Pages: 535-551 ヒトRORγリガンド結合部位，インバースアゴニストとSMRTペプチドの三者複合体結晶構造解析から，阻害剤によるコリプレッサー誘引の新規メカニズムが解明された Ternary complex of human RORγ ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment 野口　正人、野村　明弘、村瀬　賢、土井　郷樹、山口桂史、平田　和之、塩崎　真、平島　新太郎、古徳　将之、山口　尚之、勝田　佳朋、Ruo Steensma、Xioalin Li、Haiyan Tao、Bruno Tse、Morgan Fenn、Robert Babine、Erin Bradley、Paul Crowe、Scott Thacher、安達　剛、鎌田　雅史 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12494

Pages: 552-567 マイキンに結合したポロキナーゼが減数分裂期のBub1の局在を特定化する Meikin-associated polo-like kinase specifies Bub1 distribution in meiosis I 宮崎　聖良、金　智慧、山岸　有哉、石黒　伸茂、岡田　由紀、丹野　悠司、作野　剛士、渡邊　嘉典 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12496

Pages: 568-582 3T3-L1脂肪細胞においてレチノイン酸はグルコース濃度に依存してSREBP-1発現を調節し、脂肪蓄積量を変化させる Retinoic acid modulates lipid accumulation glucose concentration dependently through inverse regulation of SREBP-1 expression in 3T3L1 adipocytes Mabrouk Attia Abd Eldaim、松岡　慎也、岡松（小倉）　優子、上川　昭博、Mohamed Mohamed Ahmed、寺尾　晶、中島　恵一、木村　和弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12498

Brief Reports

Pages: 583-590 シナプス後膜周辺におけるAMPA型グルタミン酸受容体の個々のエンドサイトーシスの検出 Detection and characterization of individual endocytosis of AMPA-type glutamate receptor around postsynaptic membrane 藤井　俊平、田中　洋光、平野　丈夫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12493

Pages: 591-601 出芽酵母における母細胞と娘細胞間でのタンパク質不均等分配のプロテオミクス解析 Proteomics analysis for asymmetric inheritance of preexisting proteins between mother and daughter cells in budding yeast 岡田　充弘、楠　竣太、石橋　裕子、紀藤　圭治 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12497