Vol. 22, No. 7(July 2017)

Kyoto's Gion Matsuri is one of Japan's three greatest festivals, and its highlight is Yamahoko Junko (decorated floats' parade) in which many decorated floats with hundreds of years of tradition parade through the central part of Kyoto. Now, is the float passing by in front of us Naginata-boko that is famous for its naginata (long-handled sword) on top? No, it is the 'telomere' float. In the T-loop-like structure of the telomere extending upward on the roof, you can see two Shagumas (straw ornaments) likened to TRF1 and TRF2 bound to the double strand region and Ohata (flag) likened POT1 bound to the 3′-single-stranded overhang. These factors are comprised of the shelterin complex and need to work cooperatively and continuously for maintenance the telomere structure. Such unremitting efforts are needed to preserve not only traditions, but also telomeres.

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Genes to Cells © 2017 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 22, Issue 7, 2017.

Original Articles

Pages: 608-618 新たなERK MAPKシグナル調節剤として発見したキャビコール類縁体ACA-28はヒト悪性黒色腫細胞を選択的に殺す Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells 佐藤　亮介、萩原　加奈子、松浦　一貴、萬瀬　貴昭、喜多　綾子、久能　樹、益子　高、森山　麻里子、森山　博由、田邉　元三、村岡　修、杉浦　麗子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12499

Pages: 619-627 海洋性ビブリオ菌V. alginolyticusのべん毛形成制御因子SflAのドメインの役割とその細胞局在 Localization and domain characterization of the SflA regulator of flagellar formation in Vibrio alginolyticus 稲葉　敏、西垣　岳彦、竹川　宜宏、小嶋　誠司、本間　道夫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12501

Pages: 628-645 Thermus thermophilusの長鎖・分岐鎖ポリアミンは、高温環境下でのリボソーム、tRNA^His、tRNA^Tyrの維持に必要である Long and branched polyamines are required for maintenance of the ribosome, tRNA^His and tRNA^Tyr in Thermus thermophilus cells at high temperatures 中嶋　美沙、山上　龍太、冨川　千恵、越智　裕貴、森屋　利幸、朝原　治一、Dominique Fourmy、吉澤　聡子、大島　泰郎、堀　弘幸 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12502

Pages: 646-661 Thermoplasma acidophilum由来チロシンリコンビナーゼXerAによる試験管内部位特異的組換え In vitro site-specific recombination mediated by the tyrosine recombinase XerA of Thermoplasma acidophilum Minji Jo、村山　泰斗、筒井　康博、岩崎　博史 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12503

Brief Reports

Pages: 662-669 ショウジョウバエfat遺伝子の神経特異的ノックダウンは寿命短縮、運動能力低下、運動神経ターミナルブランチの短縮と軸索ターゲティングの異常を誘導する Neuron-specific knockdown of the Drosophila fat induces reduction of life span, deficient locomotive ability, shortening of motoneuron terminal branches and defects in axonal targeting 中村　綾、田中　領、森下　和茂、吉田　英樹、樋口　雄二郎、高嶋　博、山口　政光 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12500

Pages: 670-678 ゼブラフィッシュにおいてDcp2とCnot7は母性mRNA分解に広範かつ不均一に寄与する Pervasive yet nonuniform contributions of Dcp2 and Cnot7 to maternal mRNA clearance in zebrafish 三嶋　雄一郎、泊　幸秀 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12504