Vol. 22, No. 10(October 2017)

中心体の大名行列 気づいておくれよ脱重合
In the Edo period, feudal lords in Japan ('daimyo') had to travel back and forth between their lands and Edo (present-day Tokyo) every other year. It must have been hard for the vassals and retainers accompanied on foot. In this drawing, one prominent daimyo and his procession are depicted. The daimyo's family crest is modeled on the centrosome that acts as the main microtubule organization center in animal cells. The procession is preparing for departure from a 'honjin' (accommodation for daimyo) before dawn. It is still so dark that nobody seems to have noticed that the tips of the pole-like equipment made of microtubules have started depolymerization. They would completely depolymerized on the road unless somebody caps them with GTP-tubulins before departure.

Genes to Cells © 2017 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 22, Issue 10, 2017.

Original Articles

Pages: 850-860 Cdk1-interacting protein Cip1 is regulated by the S phase checkpoint in response to genotoxic stress Ze Zhang, Ping Ren, Ajay A. Vashisht, James A. Wohlschlegel, David G. Quintana and Fanli Zeng https://onlinelibrary.wiley.com/doi/10.1111/gtc.12518

Pages: 861-875 ヌクレオポリンNup42pのSxFG/PxFGリピートが結合したXpo1p核外輸送複合体の結晶構造 Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p 小山 昌子、平野 秀美、白井 菜月、松浦 能行 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12520

Pages: 876-884 異なる明暗スケジュールがマウスの性周期に与える影響、および夜勤による悪影響を緩和できる可能性 Effect of different light-dark schedules on estrous cycle in mice, and implications for mitigating the adverse impact of night work 芳中 貴一、山口 藍、松村 律子、野出 孝一、徳田 功、明石 真 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12522

Pages: 885-899 MFG-E8がマウス乳腺上皮細胞でインテグリン依存的に機能するためには、細胞外小胞を介した細胞外マトリクスへの局在が必要である Extracellular vesicle-mediated MFG-E8 localization in the extracellular matrix is required for its integrin-dependent function in mouse mammary epithelial cells 大石 拓弥 、灘野 大太、松田 幹、大島 健司 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12521

Pages: 900-917 GlcNAc糖鎖高分子を用いたType3中間径フィラメントの細胞表面出現とGlcNAc結合活性の解明 Elucidation of GlcNAc-binding properties of type III intermediate filament proteins, using GlcNAc-bearing polymers 伊勢 裕彦、山崎 貞徳、末吉 良成、三浦 佳子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12535

Brief Report

Pages: 918-928 細菌由来タンパク質による哺乳類細胞のリプログラミング促進 Artificial acceleration of mammalian cell reprogramming by bacterial proteins 池田 隆、内山 郁夫、岩崎 未央、佐々木 哲彦、中川 誠人、沖田 圭介、升井 伸治 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12519