Vol. 23, No. 3(March 2018)

Researchers measured the concentration of various metabolites in plasma or red blood cells taken from volunteers, and found metabolites whose concentration was specifically higher or lower in elderly individuals. In this picture, two researchers are spreading these compound structure formulae beside them, and discussing correlations of concentration between two metabolites by plotting scatter charts using a lattice of a shoji door. A bamboo fence that is likened to a clustered heatmap of metabolites can be seen over there. For drawing this image, we referred to a research paper by Chaleckis et al. (2016) Proc. Natl Acad. Sci. USA, vol. 113, pp. 4252-4259. DOI: 10.1073/pnas.1603023113.

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Genes to Cells © 2018 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 23, Issue 3, 2018.

Original Articles

Pages: 122-135 分裂酵母Lem2タンパク質の核膜局在はBqt4タンパク質との相互作用によって実現する Lem2 is retained at the nuclear envelope through its interaction with Bqt4 in fission yeast 平野　泰弘、衣笠　泰葉、淺川　東彦、近重　裕次、小布施　力史、原口　徳子、平岡　泰 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12557

Pages: 136-145 白色脂肪組織特異的amphiregulin過剰発現マウスは白色脂肪組織の縮小を呈する Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass 楊　波、久本 　高央、有馬　岳志、中村　美奈子、眞田　洋平、Thanutchaporn Kumrungsee、外丸　祐介、島田　昌之、矢中　規之 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12558

Pages: 146-160 ゲノムインプリンティング領域の正常なDNAメチル化維持に有効なES細胞培養条件 Preferable in vitro condition for maintaining faithful DNA methylation imprinting in mouse embryonic stem cells 李　知英、松沢　歩、志浦　寛相、酢谷　明人、石野　史敏 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12560

Pages: 161-171 腫瘍壊死因子-αは歯肉上皮細胞におけるヒト濾胞性樹状細胞分泌タンパク質遺伝子転写を調節する Tumor necrosis factor-α regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells 岩井　泰伸、能田　佳祐、山崎　瑞穂、加藤　彩子、目澤　優、高井　英樹、中山　洋平、小方　頼昌 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12561

Pages: 172-184 RBMXは姉妹染色分体接着に関与するセントロメアノンコーディングRNP複合体の構成因子である RBMX is a component of the centromere noncoding RNP complex involved in cohesion regulation 長裕　紀子、井手上　賢、長山　慈、荒木　令江、谷　時雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12562

Pages: 185-199 アドヘレンスジャンクションとタイトジャンクションの形成におけるl-アファディンのアクチン結合活性の役割 Requirement of the F-actin-binding activity of l-afadin for enhancing the formation of adherens and tight junctions 榊原　正太郎、丸尾　知彦、宮田　宗明、水谷　清人、高井　義美 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12566

Pages: 200-213 Cdt2のCDKリン酸化部位の変異は、ユビキチンリガーゼCRL4^Cdt2の活性を亢進する Mutations at multiple CDK phosphorylation consensus sites on Cdt2 increase the affinity of CRL4^Cdt2 for PCNA and its ubiquitination activity in S phase 貫名　康平、林　晃世、塩見　泰史、菅澤　薫、大坪　素秋、西谷　秀男 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12563

Pages: 214-224 PDGF受容体のシグナル伝達におけるNecl-5/PVRの3番目のIg様ドメインとPDGF受容体の5番目のIg様ドメインの役割 Roles of the third Ig-like domain of Necl-5/PVR and the fifth Ig-like domain of the PDGF receptor in its signaling 上田　悠貴、慶田城　迅、圓岡　真宏、水谷　清人、高井　義美 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12564

Brief Reports

Pages: 225-233 マイクロRNA-664a-5pはSH-SY5Y細胞の神経分化を促進する MicroRNA-664a-5p promotes neuronal differentiation of SH-SY5Y cells 渡邉　和則、山路　隆平、大槻　高史 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12559

Pages: 234-240 WinglessシグナルはMinute細胞競合において勝者／敗者のステータスを制御する Wingless signaling regulates winner/loser status in Minute cell competition 赤井　菜々美、井垣　達吏、大澤　志津江 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12568

Pages: 241-247 時計方向のみに回転する細菌べん毛モーターのFliG変異がFliGリング構造に及ぼす影響 Effect of a clockwise-locked deletion in FliG on the FliG ring structure of the bacterial flagellar motor 木下　実紀、難波　啓一、南野　徹 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12565

Announcement

Page: 248 編集長交代のお知らせ 柳田　充弘 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12576