Vol. 24, No. 5(May 2019)

Many people come and go across a bridge in Kyoto. Two mountains, or actually histograms can be seen at the back. These graphs are the distribution of sleep amount for male (front, 'XY') and female (back, 'XX') flies of a large number of strains in a Drosophila mutant library, and the horizontal and vertical axes represent sleep amount and frequency (the number of strains), respectively. Since many strains showed longer sleep in male than in female in this experiment, a divergence can be observed between the peaks of the histograms. For drawing this image, we referred to Cirelli et al. (2005) Nature 434, 1087-1092.

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Genes to Cells © 2019 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 24, Issue 5, 2019.

Original Articles

Pages: 338-353 細胞分裂終期の核膜孔再形成に果たすNup133とNup153および開窓膜構造の役割 Roles of Nup133, Nup153 and membrane fenestrations in assembly of the nuclear pore complex at the end of mitosis Şükriye Bilir、糀谷　知子、森　知栄、小坂田　裕子、小林　昇平、荒神　尚子、平岡　泰、原口　徳子 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12677

Pages: 354-365 SCF^Fbxw7はGSK-3によるリン酸化依存的にKLF7をユビキチン化して分解に導く SCF^Fbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation 杉山　成明、弓本　佳苗、井上　一平、中山　敬一 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12680

Pages: 366-376 ホスファチジルイノシトール特異的アラキドン酸転移酵素（LPIAT1）は細胞内Ca²⁺オシレーションに関与する Lysophosphatidylinositol-acyltrasferase-1 is involved in cytosolic Ca²⁺ oscillations in macrophages 竹増　真也、伊藤　政明、森岡　真、濁川　清美、小藤　智史、高須賀　俊輔、江口　賢史、中西　広樹、松岡　功、佐々木　純子、佐々木　雄彦、櫨木　薫 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12681

Pages: 377-389 MRG-1は線虫始原生殖細胞においてクロマチン制御による転写抑制とゲノムDNAの安定化に必要である MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans 巳波　孝至、井上　邦夫、坂本　博 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12683

Pages: 390-402 SoloのN末端Soloドメインのケラチン結合能は細胞のメカノトランスダクションに重要である Keratin-binding ability of the N-terminal Solo domain of Solo is critical for its function in cellular mechanotransduction 藤原　佐知子、松井　翼、大橋　一正、水野　健作、出口　真次 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12682