Vol. 24, No. 12(December 2019)

動画に釘付けのポスターセッション
At a poster session. A crowd is gathering around one presenter who is playing a movie on a tablet. Everybody stares at the movie. I wonder what he is showing. Something hard to resist. If only the tablet were facing this way.

Genes to Cells © 2019 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 24, Issue 12, 2019.

Meeting Report

Pages: 762-767 ゲノム編集時代における遺伝子改変動物作製技術の現在と展望:第15回トランスジェニックテクノロジー国際学会(TT2019・神戸)より Animal transgenesis now and beyond in the era of genome editing: Snapshots from the 15th Transgenic Technology Meeting (TT2019) in Kobe, Japan 清成 寛、古田 泰秀 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12725

Original Articles

Pages: 768-780 ヤマクマムシ (Hypsibius exemplaris) の乾眠誘導にはAMPK活性が必須であり、PP2Aがその上方制御因子候補である AMPK activity is required for the induction of anhydrobiosis in a tardigrade Hypsibius exemplaris, and its potential upregulator is PP2A 近藤 小雪、森 大、冨田 勝、荒川 和晴 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12726

Pages: 781-788 酵母ツーハイブリッド法を用いた相互作用欠損/減弱変異の効率的な単離法 An efficient method for the isolation of interaction-null/impaired mutants using the yeast two-hybrid technique 田中 誠司 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12724

Pages: 789-800 Lipoprotein receptor-related protein 6 is required to maintain intercalated disc integrity Xiang Wang, Yan Zou, Yang Li, Zhidan Chen, Chao Yin, Ying Wang, Lei Zhang, Jian Wu, Chunjie Yang, Guoping Zhang, Yunzeng Zou, Hui Gong https://onlinelibrary.wiley.com/doi/10.1111/gtc.12727

Pages: 801-813 T細胞受容体シグナルを介したプロテアソームの発現誘導の不全はT細胞老化の要因である Defective induction of the proteasome associated with T-cell receptor signaling underlies T-cell senescence 荒田 義之、渡邊 綾香、本杉 良、村上 龍一、後藤 剛志、堀 昌平、平山 尚志郎、濱崎 純、村田 茂穂 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12728

Pages: 814-826 Super-resolution imaging reveals changes in Escherichia coli SSB localization in response to DNA damage Tianyu Zhao, Yan Liu, Zilin Wang, Rongyan He, Jia Xiang Zhang, Feng Xu, Ming Lei, Michael B. Deci, Juliane Nguyen and Piero R. Bianco https://onlinelibrary.wiley.com/doi/10.1111/gtc.12729

Pages: 827-835 ヒト細胞を用いたRNA分解型アンチセンス(ギャップマー)のオフターゲット効果の評価手法 Evaluation of off-target effects of gapmer antisense oligonucleotides using human cells 吉田 徳幸、内藤 雄樹、安原 秀典、佐々木 澄美、川路 英哉、河合 純、内藤 幹彦、奥田 晴宏、小比賀 聡、井上 貴雄 https://onlinelibrary.wiley.com/doi/10.1111/gtc.12730

Pages: 836-847 ヒトiPS細胞由来神経幹細胞のシングル・セル解析は、異なるニューロンあるいはグリア分化能をもつ前駆細胞の存在を明らかにした Single-cell study of neural stem cells derived from human iPSCs reveals distinct progenitor populations with neurogenic and gliogenic potential Matti Lam、佐野坂 司、Anders Lundin、今泉 研人、Damla Etal、Fredrik H. Karlsson、Maryam Clausen、Jonathan Cairns、Ryan Hicks、神山 淳、Malin Kele、岡野 栄之、Anna Falk https://onlinelibrary.wiley.com/doi/10.1111/gtc.12731