Vol. 28, No. 11(November 2023)

2023-11-01 Last updated : 2025-10-17 ad_t
ルミクリンの働きで成熟する精子たち
Mouse sperm are immature immediately after production in the testis. Lumicrine factors (NELL2 and NICOL) secreted by the testis stimulate the differentiation of epididymal initial segment epithelial cells, and these epithelial cells are responsible for processing the ADAM3 protein on the sperm surface, resulting in sperm maturation. For details, see the review article in this issue (Kiyozumi (2023) Genes Cells 28: 757-763, DOI: 10.1111/gtc.13066). The boys with long hair in this drawing also have their hair cut at the barbershops at the approach to a bridge and go out into the world, crossing the bridge as mature men.
Genes to Cells © 2023 the Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

Volume 28, Issue 11, 2023.

Review Article

Pages: 757-763 ルミクリンシグナル伝達：生殖路管腔を通じた精子成熟制御の細胞外機構 Lumicrine signaling: Extracellular regulation of sperm maturation in the male reproductive tract lumen 淨住　大慈 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13066

Original Articles

Pages: 764-775 Wnt10b knockdown promotes UCP1 expression in brown adipose tissue in mice Yanxin Jia, Yan Liu, Shuang Liu, Yaxin Chang, Longfei Xu and Haifang Li https://onlinelibrary.wiley.com/doi/10.1111/gtc.13064 Pages: 776-788 腸管上皮細胞におけるIL-23/IL-22を介した遺伝子発現制御は、小腸と大腸とで腸内細菌叢への依存性が異なる Differential dependence on microbiota of IL-23/IL-22-dependent gene expression between the small- and large-intestinal epithelia 中谷　彩香、奥村　龍、石橋　亜衣里、岡本　翔太、榊　渓、伊藤　裕貴、奥﨑　大介、猪原　秀典、竹田　潔 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13065 Pages: 789-799 酵母トア複合体１はeIF4E結合タンパク質Caf20をリン酸化する Yeast Tor complex 1 phosphorylates eIF4E-binding protein, Caf20 鎌田　芳彰、安東　稜子、井沢　真吾、松浦　彰 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13067 Pages: 800-810 単一細胞トランスクリプトーム解析のためのプラナリア生細胞のFACSによる単離法の確立 Isolation of planarian viable cells using fluorescence-activated cell sorting for advancing single-cell transcriptome analysis 黒木　義人、阿形　清和 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13068 Pages: 811-820 常染色体顕性多発性嚢胞腎原因タンパク質Pkd2は、分裂酵母において小胞体に局在し、カルシウムシグナルの活性化に関わる Pkd2, mutations linking to autosomal dominant polycystic kidney disease, localizes to the endoplasmic reticulum and regulates calcium signaling in fission yeast 古家野　孝行、藤本　尭玄、大西　香織、松山　誠、福島　正樹、久米　一規 https://onlinelibrary.wiley.com/doi/10.1111/gtc.13069
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