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IPR invites qualified applicants to fill the following position:

IPR is a research institute that conducts multidisciplinary life science researches on structures and functions of proteins using creative and innovative approaches. IPR also contributes to the scientific community as a Joint-Usage/Research Center, which promotes collaborative research activities with domestic and international scientists. In order to develop above-mentioned activities as well as to explore a new area of life science research, IPR is seeking for a competitive researcher in one of its division (Division of Protein Structural Biology) as a PI (Professor or associate professor). IPR is particularly seeking for an internationally recognized candidate capable of conducting creative research in structural biology based on the cutting-edge cryo-EM as well as supporting the activity of Joint-Usage/Research at IPR.

Position; Professor or Associate Professor 1 Person

Affiliation; Division of Protein Structural Biology, Institute for Protein Research

Job description;

1. Conducting research in the area of expertise described above

2. Supporting the activity of Joint-Usage/Research Center as an PI responsible for the cryo-EM facility

3. Teaching undergraduate students from School of Science, and graduate students from Graduate School of Science and/or Frontier Biosciences of Osaka University.

4. Participating in the administrative committees in IPR and Osaka University.

Start of employment;
October 1, 2019 or earliest date after that

Employment: Tenured full professor or associate professor

Condition: To be given a research space as well as one assistant professor position

Qualification: PhD holder in the relevant fields with more than 5 years research experiences after obtaining the degree.

Deadline of the application: June 10th (Monday), 2019.

Documents to be submitted:

1. CV with photograph and e-mail (contacting address) including job history and awards

2. List of publications* (papers, reviews and books) with the citation index; list of presentations (invited talks only) ; Citation index (h-index) in Google Scholar**. Encircle the numbers of the most important papers (up to 5).

3. List of scientific external grants during the past 10 years (2009-2019)

4. Description on i) Past research and achievement; ii) Future plan of researches and their perspectives; iii) Past experiences of teaching and contribution to a Joint-Usage/Research, if any (up to 6 pages in total).

5. Summaries for the most important papers (up to 5) in no more than 400 words each.

6. PDF reprints of the above five important papers.

7. Letter of recommendation from two researchers, who directly know the candidate well.

*Authors, title, name of journal, volume, pages, years should be included, with the applicant’s name underlined.

**The h-index will be obtained in “Google Scholar”; please register and create your own account at the site. In “My citation” page, after selecting your own papers, the citation number, h-index and i10 index are automatically calculated and will be shown in the upper right corner of the page. Please indicate the numbers (citation number, h-index and i10 index) in the List of publication.

Please prepare the documents 1-5 in either A4 or legal size, and save them as a single combined PDF file. Save this file as well as the PDF reprints (document #6) in an electronic media (CD, DVD etc.) and mail it to the address below via regular post. A recommendation letter should be in a sealed envelope when included in the application package, or can be directly sent to the Office in an envelope with a clear indication about the content.

Notes:
CV and other documents should be written either in English or Japanese.
Application documents will not be returned.

Application address:
Please send the application to the following address as the registered mail and write on the envelope in red ink: Application for Professor of IPR”.

Address:
Office of General affairs
3-2 Yamadaoka Suita, Osaka 565-0871
Tel: +81-(0)6-6879-8594

Enquiry about the position:
Genji Kurisu, Professor, a chair for the election committee
Tel: +81-(0)6-6879-8604
E-mail: gkurisu[a]protein.osaka-u.ac.jp (change [a] to @).

Additional Information:

(1) The term of Employment
No Fixed Term

(2) Probation Period
6 months

(3) Work Location
Suita Campus (3-2 Yamadaoka Suita, Osaka 565-0871)

(4) Employment Form
The discretionary Labor System, Special Work Type is applied. (Deemed working hours: 8 hours a day) *Based on the ‘Regulations Pertaining to Working Hours, Holidays and Leave for National University Corporation Osaka University Staff.’

(5) Salary and Benefits
Based on the “Salary Regulations for National University Corporation Osaka University Staff”

(6) Insurance
Successful candidate will join National Public Service Personnel Mutual Aid Associations, Employment Insurance and Workers’ Accident Compensation Insurance.

(7) Concerning work conditions, please refer to “Work Regulations for National University Corporation Osaka University Staff” and related regulations.
https://www.osaka-u.ac.jp/en/guide/information/joho/kitei_shugyou.html

Recruiter:
National University Corporation Osaka University

2019-04-15 2019-06-10

See our websitefor details: http://www.riken.jp/en/careers/hakubi/sechikato2020/

RIKEN offers up to one junior Principal Investigator (PI) position, a RIKEN Hakubi Fellow position, for an exceptionally talented female researcher for a maximum of 7 years in the framework of the Sechi Kato Program. The RIKEN Hakubi Fellow is expected to engage in creative and ambitious research in natural and mathematical sciences, including research areas bordering the humanities and social sciences, by leading her independent research team. Proposals intended to resolve urgent issues that humankind faces today are also welcome (See for example, Sustainable Development Goals of United Nations).
One of the important goals of the RIKEN Haubi Fellows Program is to foster stimulating interactions among the Fellows with diverse backgrounds and to create an intellectual hub of scientists with different disciplines within and beyond RIKEN.

*Who is Sechi Kato? — Sechi Kato (1893-1989) is a pioneering female scientist who developed spectrometric analysis of organic materials in Japan, and the first female Chief Scientist of RIKEN.

*What is “Hakubi”? — Hakubi is a proverb derived from classical Chinese literature.
There were five siblings in ancient China, all excellent, but the most brilliant one had white (haku) eyebrows (bi).

Qualifications
Applicants should be talented female researchers who are able to engage in research at RIKEN on a full-time basis with the ability to manage their research laboratories as PIs. A doctoral degree is not necessarily required for this position.

Research environment
In addition to the salary, a successful candidate will be allocated a research budget of 10 to 40 million yen per year depending on the research plan and the progress. The Hakubi Fellow is assigned a laboratory space of about 150 square meters in total at Wako campus or, if considered necessary, at one of RIKEN’s branches in Japan. The final details will be decided through discussions with the Hakubi Fellows Program Head.

Term of employment and salary
Employment starts on April, 2020 or later and the contract period is up to a total of 5 years. Upon evaluation the period can be extended for additional 2 years, for a maximum of 7 years.
The annual salary is approximately 10 million yen per year (including tax). In addition, commuting and housing allowances are provided according to the RIKEN regulations.

Application and screening procedures
Apply online through Application procedures.
Applicants of the Sechi Kato Program may also apply for the regular Hakubi Fellows Program.
The first stage of screening is an evaluation of submitted documents, the results of which is notified by early September. Successful applicants then proceed to the second stage, the interview, which is currently scheduled to take place in autumn.

Deadline
Online registration: 24:00 (JST), June 14, 2019
Upload of application documents: 15:00 (JST), June 28, 2019

Contact Information
RIKEN Hakubi Desk,
Research Personnel Affairs Section, RIKEN
hakubi@riken.jp

2019-04-08 2019-06-14

See our website for details: http://www.riken.jp/en/careers/hakubi/hakubi2020/

RIKEN offers junior Principal Investigator (PI) positions, the RIKEN Hakubi Fellows, for exceptionally talented researchers for a maximum of 7 years. RIKEN Hakubi Fellows are expected to engage in creative and ambitious research in natural and mathematical sciences, including research areas bordering the humanities and social sciences, by leading their independent research teams. Proposals intended to resolve urgent issues that humankind faces today are also welcome (See for example, Sustainable Development Goals of United Nations).
One of the important goals of the RIKEN Hakubi Fellows Program is to foster stimulating interactions among the Fellows with diverse backgrounds and to create an intellectual hub of scientists with different disciplines within and beyond RIKEN.
Up to two Hakubi Fellow positions are offered this year. See RIKEN Hakubi Fellows appointed in 2018 and 2019.

*What is “Hakubi”? — Hakubi is a proverb derived from classical Chinese literature.
There were five siblings in ancient China, all excellent, but the most brilliant one had white (haku) eyebrows (bi).

Qualifications
Applicants should be talented researchers who are able to engage in research at RIKEN on a full-time basis with the ability to manage their laboratories as PIs. A doctoral degree is not necessarily required for this position.

Research environment
In addition to the salary, a successful candidate will be allocated a research budget of 10 to 40 million yen per year depending on the research plan and the progress. The Hakubi Fellow is assigned a laboratory space of about 150 square meters in total at Wako campus or, if considered necessary, at one of RIKEN’s branches in Japan. The final details will be decided through discussions with the Hakubi Fellows Program Head.

Term of employment and salary
Employment starts on April, 2020 or later and the contract period is up to a total of 5 years. Upon evaluation the period can be extended for additional 2 years, for a maximum of 7 years.
The annual salary is approximately 10 million yen per year (including tax). In addition, commuting and housing allowances are provided according to the RIKEN regulations.

Application and screening procedures
The first stage of screening is an evaluation of submitted documents, the results of which is notified by early September. Successful applicants then proceed to the second stage, the interview, which is currently scheduled to take place in autumn.

Deadline
Online registration: 24:00 (JST), June 14, 2019
Upload of application documents: 15:00 (JST), June 28, 2019

Contact Information
RIKEN Hakubi Desk,
Research Personnel Affairs Section, RIKEN
hakubi@riken.jp

2019-04-08 2019-06-14

A postdoctoral position is now available in the Department of Pharmacology in the School of Medicine at Case Western Reserve University. The laboratory is currently funded by the NIH and a private foundation that focuses on Usher Syndrome. Our research focus is retinal cell biology with the goal of discovering small molecule therapy for photoreceptor degenerative disorders. To elucidate the disease mechanisms, we genetically dissect the process of photoreceptor morphogenesis and maintenance in vertebrate animals. Our laboratory pioneered real-time imaging of proteins and small molecules within the retina, and takes advantage of state of the art confocal/multiphoton/STED microscopy techniques. Our research also heavily depends on the tissue culture system to biochemically study the components required for photoreceptor morphogenesis/maintenance. For more details, check our website: https://www.imanishi-lab.org

The applicant is expected to be highly independent and be capable of designing experiments and conducting hypothesis-based research projects. The candidate should have a strong background in cell biology, molecular biology, or biochemistry. Knowledge of fluorescence microscopy is favorable, although not necessary. Salary will be commensurate with experience and will adhere to current NIH guidelines.
Please submit your CV, brief statement of research interest, and contact information for three references via E-mail to Dr. Yoshikazu Imanishi (yxi19@case.edu).

2019-04-05 2019-07-05

Job Description:
The lab led by Professor Hiroyuki Nakai, M.D., Ph.D. is seeking a highly motivated and enthusiastic post-doctoral fellow who is willing to lead the project aimed at developing novel AAV vector-mediated gene therapy for renal diseases. The Nakai lab is in the Departments of Molecular & Medical Genetics and Molecular Microbiology & Immunology, Oregon Health & Science University (OHSU) School of Medicine in Portland (Oregon, USA). The lab is also affiliated with the Oregon National Primate Research Center (ONPRC). The successful candidate will join the project where we seek to establish novel mouse models for renal diseases using the CRISPR technology, develop novel AAV vectors using our unpublished technology called TRAnscription/TRAnslation-dependent Directed Evolution (TRADE), comprehensively study novel AAV vectors using AAV Barcode-Seq combined with snRNA-seq, and assess their therapeutic efficacy in animal models for renal diseases.

Required Qualifications:

- Doctoral degree in a relevant field

- Substantial knowledge and expertise in molecular biology and research of renal diseases.

- Ability to perform multiple tasks and prioritize them

- Ability to organize and handle a large quantity of data

- Excellent creative thinking skills

- Excellent verbal and written communication skills

- Strong enthusiasm for AAV and gene therapy research

Salary Range:
$50,004+ Commensurate with experience

How to apply:
Please send a cover letter and C.V. to
Hiroyuki Nakai, M.D., Ph.D.
Professor
Department of Molecular and Medical Genetics
Department of Molecular Microbiology and Immunology
Email: nakaih@ohsu.edu

Oregon Health & Science University values a diverse and culturally competent workforce. We are proud of our commitment to being an equal opportunity, affirmative action organization that does not discriminate against applicants on the basis of any protected class status, including disability status and protected veteran status. Individuals with diverse backgrounds and those who promote diversity and a culture of inclusion are encouraged to apply. To request reasonable accommodation, contact the Affirmative Action and Equal Opportunity Department at 503-494-5148 or aaeo@ohsu.edu.

2019-03-11 2019-06-11

The Posfai Lab (www.posfailab.org) at Princeton University is looking to recruit a highly motivated postdoctoral fellow. Our group studies the molecular and cellular mechanisms of cell fate choice and morphogenesis during early embryonic development, using the preimplantation mouse embryo as a model system. Our main approach is combining genetic engineering and quantitative, high-resolution live imaging using light sheet microscopy. The lab’s assets include our recently developed highly efficient genome editing method in mouse embryos and our own light sheet microscope dedicated to preimplantation embryo imaging.

The postdoctoral candidate should have a strong interest in developmental biology and mouse genetics. Experience in light sheet microscopy and/or computational image analysis is preferred, but not necessary. Motivation and excellence is valued more than previous field of study.

The candidate will benefit from an interdisciplinary and collaborative environment at Princeton and the vibrant and supportive atmosphere of a junior lab. Researchers at the rank of Postdoctoral Research Associate are ordinarily appointed for one year at a time. Appointments are reviewed annually to consider reappointment and salary level. The position is benefits-eligible.

To apply, email your CV and cover letter explaining your interests and motivation to Eszter Posfai (eposfai@princeton.edu) and arrange for three reference letters to be sent on your behalf.

For more information, visit www.posfailab.org.

2019-02-22 2019-05-22

The Kojima Lab is looking for a highly motivated Postdoctoral Associate to work on a NIH-funded project that dissects molecular functions of a novel non-coding gene in the mammalian circadian system. We are looking for ambitious, creative and smart colleagues, whose expertise enriches our team.

Required Qualifications include: 1) Ph.D. degree in biochemistry, biology, or a related field, 2) One or more publication as a first-author in a peer-reviewed journal, 3) Experience in at least one of the following fields (molecular/cellular biology, generation of genetically modified animal models, RNA biology). Experiences in bioinformatics and/or mathematical modeling of molecular regulatory networks will be appreciated.

This position carries a salary of $45,000 – $58,850 (depending on experience) plus benefits, including health insurance. Review of applications will begin immediately until the positions are filled. To apply, please submit a cover letter discussing your interest in a position, your curriculum vitae, a half-page research statement, and contact information for three references at: https://listings.jobs.vt.edu/postings/94635

Further inquiries should be directed to Shihoko Kojima (skojima@vt.edu). Our laboratory is committed to promoting diversity and inclusion at Virginia Tech, and we welcome applications by individuals with disabilities, or members of minorities or other disadvantaged groups.

2019-02-15 2019-05-15

The Thymus Biology Section in the Experimental Immunology Branch, CCR, NCI, NIH, focuses on the mechanisms how the thymic microenvironments contribute to the development of functionally potent and self-tolerant T cells. We are particularly interested in studying how the diversity in thymic epithelial cells develops, how thymic epithelial cell subpopulations contribute to functional-tuning and self-tolerance in T cells, and how the thymic microenvironments sequentially guide the position of developing T cells to optimize their development and selection. Unveiling the thymic machinery in these processes will aid future therapies.

Our recent contributions include: Murata et al. Nat Immunol. 2018; Sakata et al. J Immunol. 2018; Kozai et al. J Exp Med. 2017; Ohigashi et al. JCI Insight. 2017; Uddin et al. Nat Commun. 2017; Takahama et al. Nat Rev Immunol. 2017; Ohigashi et al. Cell Rep. 2015; Takada et al. Nat Immunol. 2015; and Sasaki et al. Nat Commun. 2015.

We look for a self-motivated and enthusiastic scientist with a recent Ph.D. or M.D. Experience in immunology, developmental biology, and molecular biology is desirable.

Interested applicants should send a curriculum vitae, the names of three references, and a brief summary of their previous research and future goals to yousuke.takahama@nih.gov. Review of applications will begin immediately and continue until the position is filled.

Yousuke Takahama, Ph.D.
Senior Investigator
Thymus Biology Section
Experimental Immunology Branch
Center for Cancer Research
National Cancer Institute
National Institutes of Health
Building 10 Room 4B10
Bethesda, Maryland 20892
Phone: 240-858-3223
Email: yousuke.takahama@nih.gov
https://ccr.cancer.gov/Experimental-Immunology-Branch/yousuke-takahama

2019-02-05 2019-05-05

A postdoctoral position available in the Shcheglovitov Lab at the University of Utah to study the biochemical and functional properties of human neurons and organoids derived from patient-specific and CRISPR/Cas9-engineered induced pluripotent stem cells for modeling autism, intellectual disability, and epilepsy. We particularly invite applications from ambitious, exquisite, and motivated individuals with substantial neuroscience-related experience in molecular biology, biochemistry, physiology, or imaging. The work in our lab is currently centered around two NIH-funded research projects:

Project 1: Cellular and molecular mechanisms disrupted in 22q13 deletion syndrome and autism. We previously demonstrated that SHANK3-deficient human cortical neurons derived from induced pluripotent stem cells (iPSCs) acquired from 22q13 deletion syndrome patients with autism and intellectual disability have severely impaired excitatory synaptic transmission (Shcheglovitov et al., Nature 2013). However, the cellular and molecular mechanisms responsible for the development of these deficits remain unknown. The main goal of this project is to elucidate the cellular and molecular mechanisms responsible for the development of synaptic and connectivity deficits in SHANK3-deficient human neurons.

Project 2: Mechanisms of epilepsy in human neurodevelopmental disorders: focus on 22q13 deletion syndrome. Epilepsy is a major source of morbidity and mortality associated with autism. However, the cellular and molecular mechanisms responsible for epilepsy in these individuals remain largely unknown. We have developed a new method for making human cortical organoids with functional neural networks from induced pluripotent stem cells (iPSC) and generated iPSCs from 22q13 deletion syndrome patients with drug-resistant epilepsy. The main goal of this project is to investigate the cellular and molecular mechanisms of drugresistant epilepsy using cortical organoids derived from iPSCs obtained from 22q13 deletion syndrome patients with drug-resistant epilepsy.

The University of Utah is one of the largest Research University in the American Midwest. It is located in Salt Lake City in the foothills of the Wasatch Mountains with several famous Ski Resorts and National Parks nearby. The university offers vibrant research environment with multiple state-of-art core research facilities and numerous interdisciplinary centers and initiatives, including NIH Center for Clinical and Translational Research, NIH Anticonvulsant Drug Development Program, Utah Neuroscience Initiative, and Utah Genome Project Initiative, to support innovative biomedical research.
The Department of Neurobiology and Anatomy is a highly collegial and collaborative department heavily invested in the “cutting-edge” neuroscience research. It provides exceptional mentoring support for postdocs interested in both academia and industry.

If you are interested in this opportunity, please email your CV and cover letter briefly describing your research interests to Dr. Alex Shcheglovitov (alexsh@neuro.utah.edu).

2019-02-01 2019-05-01

The Srinivasan Lab at Oklahoma Medical Research Foundation (OMRF) studies lymphedema, a debilitating disease for which there is no cure. The lab uses state of the art technologies to dissect the roles of transcription factors and signaling molecules. We collaborate with numerous internationally recognized investigators thus offering career development opportunities for trainees. Please check our latest publications: Geng et al (2016) Dev Biol. (cover image) Jan 1;409(1):218-33, Cha et al (2016) Genes Dev. (cover image) June 16; 30: 1-16, and Cha et al (2018) Cell Reports (cover image) October 16; 25(3):571-584.
More information about our lab can be found at
https://omrf.org/researchfaculty/scientists/srinivasan-sathish/
We are recruiting highly motivated researchers who are interested in Cell biology and Biochemistry.

Required Qualifications
Ph.D., M.D., or Ph.D./M.D.,
Fresh graduates will be considered for postdoctoral fellowships, and more experienced researchers will be considered for the position of Staff Scientist. Salary of postdoctoral fellows is according to the stipulation of NIH. Salary of the Staff Scientist will be commensurate with experience. Only candidates with at least one first author publication in respected journals of Cell Biology or Biochemistry would be considered for the positions.
Please send CV, list of 3 references, reprints of publications and a brief summary of interests and career goals to Sathish-srinivasan@omrf.org.
OMRF is an independent, not-for-profit, biomedical research institute in Oklahoma City, USA. OMRF has been selected as one of the best research institutions for post-docs from 2011 to 2013 in the USA by The Scientist journal. Oklahoma City metropolitan area offers affordable housing, low cost of living, great public schools and numerous recreational activities. Additional information about OMRF can be found at https://omrf.org/.

2018-12-14 2019-06-14